{ "cells": [ { "cell_type": "markdown", "metadata": {}, "source": [ "# Cell Cycle genes\n", "Using Gene Ontologies (GO), create an up-to-date list of all human protein-coding genes that are know to be associated with cell cycle." ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "## 1. Download Ontologies, if necessary" ] }, { "cell_type": "code", "execution_count": 1, "metadata": {}, "outputs": [ { "name": "stdout", "output_type": "stream", "text": [ " EXISTS: go-basic.obo\n" ] } ], "source": [ "# Get http://geneontology.org/ontology/go-basic.obo\n", "from goatools.base import download_go_basic_obo\n", "obo_fname = download_go_basic_obo()" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "## 2. Download Associations, if necessary" ] }, { "cell_type": "code", "execution_count": 2, "metadata": {}, "outputs": [ { "name": "stdout", "output_type": "stream", "text": [ " EXISTS: gene2go\n" ] } ], "source": [ "# Get ftp://ftp.ncbi.nlm.nih.gov/gene/DATA/gene2go.gz\n", "from goatools.base import download_ncbi_associations\n", "gene2go = download_ncbi_associations()" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "## 3. Read associations\n", "Normally, when reading associations, GeneID2GOs are returned. We get the reverse, GO2GeneIDs, by adding the key-word arg, \"go2geneids=True\" to the call to read_ncbi_gene2go." ] }, { "cell_type": "code", "execution_count": 3, "metadata": {}, "outputs": [ { "name": "stdout", "output_type": "stream", "text": [ "HMS:0:00:05.295771 323,107 annotations, 19,649 genes, 18,246 GOs, 1 taxids READ: gene2go \n", "12285 IDs in loaded association branch, BP\n", "12285 GO terms associated with human NCBI Entrez GeneIDs\n" ] } ], "source": [ "from goatools.anno.genetogo_reader import Gene2GoReader\n", "\n", "objanno = Gene2GoReader(\"gene2go\", taxids=[9606])\n", "go2geneids_human = objanno.get_id2gos(namespace='BP', go2geneids=True)\n", "\n", "print(\"{N:} GO terms associated with human NCBI Entrez GeneIDs\".format(N=len(go2geneids_human)))" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "## 4. Initialize Gene-Search Helper" ] }, { "cell_type": "code", "execution_count": 4, "metadata": {}, "outputs": [ { "name": "stdout", "output_type": "stream", "text": [ "go-basic.obo: fmt(1.2) rel(2020-01-01) 47,337 GO Terms; optional_attrs(comment def relationship synonym xref)\n" ] } ], "source": [ "from goatools.go_search import GoSearch\n", "\n", "srchhelp = GoSearch(\"go-basic.obo\", go2items=go2geneids_human)" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "## 5. Find human all genes related to \"cell cycle\"" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "### 5a. Prepare \"cell cycle\" text searches\n", "We will need to search for both *cell cycle* and *cell cycle-independent*. Those GOs that contain the text *cell cycle-independent* are specifically **not** related to *cell cycle* and must be removed from our list of *cell cycle* GO terms." ] }, { "cell_type": "code", "execution_count": 5, "metadata": {}, "outputs": [], "source": [ "import re\n", "\n", "# Compile search pattern for 'cell cycle'\n", "cell_cycle_all = re.compile(r'cell cycle', flags=re.IGNORECASE)\n", "cell_cycle_not = re.compile(r'cell cycle.independent', flags=re.IGNORECASE)" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "### 5b. Find NCBI Entrez GeneIDs related to \"cell cycle\"" ] }, { "cell_type": "code", "execution_count": 6, "metadata": {}, "outputs": [ { "name": "stdout", "output_type": "stream", "text": [ "2062 human NCBI Entrez GeneIDs related to 'cell cycle' found.\n" ] } ], "source": [ "# Find ALL GOs and GeneIDs associated with 'cell cycle'.\n", "\n", "# Details of search are written to a log file\n", "fout_allgos = \"cell_cycle_gos_human.log\" \n", "with open(fout_allgos, \"w\") as log:\n", " # Search for 'cell cycle' in GO terms\n", " gos_cc_all = srchhelp.get_matching_gos(cell_cycle_all, prt=log)\n", " # Find any GOs matching 'cell cycle-independent' (e.g., \"lysosome\")\n", " gos_no_cc = srchhelp.get_matching_gos(cell_cycle_not, gos=gos_cc_all, prt=log)\n", " # Remove GO terms that are not \"cell cycle\" GOs\n", " gos = gos_cc_all.difference(gos_no_cc)\n", " # Add children GOs of cell cycle GOs\n", " gos_all = srchhelp.add_children_gos(gos)\n", " # Get Entrez GeneIDs for cell cycle GOs\n", " geneids = srchhelp.get_items(gos_all)\n", "print(\"{N} human NCBI Entrez GeneIDs related to 'cell cycle' found.\".format(N=len(geneids)))\n" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "## 6. Print the \"cell cycle\" protein-coding gene Symbols\n", "In this example, the background is all human protein-codinge genes. \n", "\n", "Follow the instructions in the `background_genes_ncbi` notebook to download a set of background population genes from NCBI." ] }, { "cell_type": "code", "execution_count": 7, "metadata": {}, "outputs": [], "source": [ "from genes_ncbi_9606_proteincoding import GENEID2NT" ] }, { "cell_type": "code", "execution_count": 8, "metadata": {}, "outputs": [ { "name": "stdout", "output_type": "stream", "text": [ "RNF212B ring finger protein 212B\n", "TTYH1 tweety family member 1\n", "CABLES2 Cdk5 and Abl enzyme substrate 2\n", "SEH1L SEH1 like nucleoporin\n", "KIF18A kinesin family member 18A\n", "CHAF1B chromatin assembly factor 1 subunit B\n", "SDE2 SDE2 telomere maintenance homolog\n", "ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase\n", "CLTCL1 clathrin heavy chain like 1\n", "AICDA activation induced cytidine deaminase\n", "USP9X ubiquitin specific peptidase 9 X-linked\n", "SMC1A structural maintenance of chromosomes 1A\n", "HIPK1 homeodomain interacting protein kinase 1\n", "ACTA1 actin alpha 1, skeletal muscle\n", "ACTB actin beta\n", "SPC25 SPC25 component of NDC80 kinetochore complex\n", "NAA10 N-alpha-acetyltransferase 10, NatA catalytic subunit\n", "ACVR1 activin A receptor type 1\n", "ACVR1B activin A receptor type 1B\n", "TUBGCP5 tubulin gamma complex associated protein 5\n", "BIRC6 baculoviral IAP repeat containing 6\n", "ADARB1 adenosine deaminase RNA specific B1\n", "LIN9 lin-9 DREAM MuvB core complex component\n", "ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1\n", "ADCYAP1 adenylate cyclase activating polypeptide 1\n", "MYORG myogenesis regulating glycosidase (putative)\n", "AXIN2 axin 2\n", "BAP1 BRCA1 associated protein 1\n", "CDC7 cell division cycle 7\n", "CDC45 cell division cycle 45\n", "CNOT6 CCR4-NOT transcription complex subunit 6\n", "FZD9 frizzled class receptor 9\n", "GFI1B growth factor independent 1B transcriptional repressor\n", "GMNC geminin coiled-coil domain containing\n", "SYCE1L synaptonemal complex central element protein 1 like\n", "NLN neurolysin\n", "MTA3 metastasis associated 1 family member 3\n", "HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2\n", "RPTOR regulatory associated protein of MTOR complex 1\n", "KLHL13 kelch like family member 13\n", "HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1\n", "MAD1L1 mitotic arrest deficient 1 like 1\n", "AHR aryl hydrocarbon receptor\n", "KLHL42 kelch like family member 42\n", "AIF1 allograft inflammatory factor 1\n", "TP53I13 tumor protein p53 inducible protein 13\n", "AKT1 AKT serine/threonine kinase 1\n", "AKT2 AKT serine/threonine kinase 2\n", "MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3\n", "TAOK1 TAO kinase 1\n", "UXT ubiquitously expressed prefoldin like chaperone\n", "CEP126 centrosomal protein 126\n", "RAD54L RAD54 like\n", "ALOX15B arachidonate 15-lipoxygenase type B\n", "DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3\n", "DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2\n", "CUL4B cullin 4B\n", "CUL4A cullin 4A\n", "CUL3 cullin 3\n", "CUL2 cullin 2\n", "CUL1 cullin 1\n", "TICRR TOPBP1 interacting checkpoint and replication regulator\n", "KLF11 Kruppel like factor 11\n", "BIN1 bridging integrator 1\n", "FKBP6 FKBP prolyl isomerase 6\n", "RAE1 ribonucleic acid export 1\n", "OFD1 OFD1 centriole and centriolar satellite protein\n", "ANK3 ankyrin 3\n", "C6orf89 chromosome 6 open reading frame 89\n", "PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D\n", "ANXA1 annexin A1\n", "USP28 ubiquitin specific peptidase 28\n", "KLHL40 kelch like family member 40\n", "KNSTRN kinetochore localized astrin (SPAG5) binding protein\n", "PKP4 plakophilin 4\n", "APAF1 apoptotic peptidase activating factor 1\n", "USP29 ubiquitin specific peptidase 29\n", "APBB1 amyloid beta precursor protein binding family B member 1\n", "CDKL4 cyclin dependent kinase like 4\n", "APC APC regulator of WNT signaling pathway\n", "APBB2 amyloid beta precursor protein binding family B member 2\n", "APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1\n", "BIRC2 baculoviral IAP repeat containing 2\n", "GAS7 growth arrest specific 7\n", "BIRC5 baculoviral IAP repeat containing 5\n", "TRIM71 tripartite motif containing 71\n", "CAMK1 calcium/calmodulin dependent protein kinase I\n", "BARX2 BARX homeobox 2\n", "USP37 ubiquitin specific peptidase 37\n", "APP amyloid beta precursor protein\n", "FAS Fas cell surface death receptor\n", "FASLG Fas ligand\n", "MAPKAPK5 MAPK activated protein kinase 5\n", "PIAS1 protein inhibitor of activated STAT 1\n", "CDC14B cell division cycle 14B\n", "CDC14A cell division cycle 14A\n", "KIAA1614 KIAA1614\n", "CDK10 cyclin dependent kinase 10\n", "GADD45GIP1 GADD45G interacting protein 1\n", "THOC5 THO complex 5\n", "ARF1 ADP ribosylation factor 1\n", "MADD MAP kinase activating death domain\n", "ARF6 ADP ribosylation factor 6\n", "SPC24 SPC24 component of NDC80 kinetochore complex\n", "RHOA ras homolog family member A\n", "RHOB ras homolog family member B\n", "RHOC ras homolog family member C\n", "ARL2 ADP ribosylation factor like GTPase 2\n", "ARL3 ADP ribosylation factor like GTPase 3\n", "ARNTL aryl hydrocarbon receptor nuclear translocator like\n", "CCDC124 coiled-coil domain containing 124\n", "CNOT6L CCR4-NOT transcription complex subunit 6 like\n", "RUVBL1 RuvB like AAA ATPase 1\n", "KASH5 KASH domain containing 5\n", "HAUS1 HAUS augmin like complex subunit 1\n", "CDC26 cell division cycle 26\n", "ASCL1 achaete-scute family bHLH transcription factor 1\n", "CDK13 cyclin dependent kinase 13\n", "TP63 tumor protein p63\n", "STK33 serine/threonine kinase 33\n", "ASNS asparagine synthetase (glutamine-hydrolyzing)\n", "MARK4 microtubule affinity regulating kinase 4\n", "SSNA1 SS nuclear autoantigen 1\n", "ASPH aspartate beta-hydroxylase\n", "PHACTR4 phosphatase and actin regulator 4\n", "BRINP2 BMP/retinoic acid inducible neural specific 2\n", "DDRGK1 DDRGK domain containing 1\n", "LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3\n", "POLD4 DNA polymerase delta 4, accessory subunit\n", "CCAR2 cell cycle and apoptosis regulator 2\n", "DYNLL1 dynein light chain LC8-type 1\n", "ZFHX3 zinc finger homeobox 3\n", "TNKS tankyrase\n", "ATM ATM serine/threonine kinase\n", "CCNB1IP1 cyclin B1 interacting protein 1\n", "RBM24 RNA binding motif protein 24\n", "BECN1 beclin 1\n", "PEA15 proliferation and apoptosis adaptor protein 15\n", "ATP2B4 ATPase plasma membrane Ca2+ transporting 4\n", "BOLL boule homolog, RNA binding protein\n", "CDC23 cell division cycle 23\n", "TRADD TNFRSF1A associated via death domain\n", "TPRA1 transmembrane protein adipocyte associated 1\n", "EED embryonic ectoderm development\n", "GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1\n", "ATR ATR serine/threonine kinase\n", "ATRX ATRX chromatin remodeler\n", "CRADD CASP2 and RIPK1 domain containing adaptor with death domain\n", "TNFSF14 TNF superfamily member 14\n", "RIPK1 receptor interacting serine/threonine kinase 1\n", "TNFSF10 TNF superfamily member 10\n", "AVPR1A arginine vasopressin receptor 1A\n", "STAC3 SH3 and cysteine rich domain 3\n", "BACH1 BTB domain and CNC homolog 1\n", "BAD BCL2 associated agonist of cell death\n", "RAB11A RAB11A, member RAS oncogene family\n", "ADGRB1 adhesion G protein-coupled receptor B1\n", "MEIOB meiosis specific with OB-fold\n", "ADGRB2 adhesion G protein-coupled receptor B2\n", "BAK1 BCL2 antagonist/killer 1\n", "RIPK2 receptor interacting serine/threonine kinase 2\n", "FADD Fas associated via death domain\n", "BAX BCL2 associated X, apoptosis regulator\n", "BARD1 BRCA1 associated RING domain 1\n", "BBS4 Bardet-Biedl syndrome 4\n", "BCAT1 branched chain amino acid transaminase 1\n", "CCND1 cyclin D1\n", "BCL2 BCL2 apoptosis regulator\n", "BCL2L1 BCL2 like 1\n", "BCL3 BCL3 transcription coactivator\n", "TNFRSF10B TNF receptor superfamily member 10b\n", "BCL6 BCL6 transcription repressor\n", "TNFRSF10A TNF receptor superfamily member 10a\n", "BCL9 BCL9 transcription coactivator\n", "BCR BCR activator of RhoGEF and GTPase\n", "CCNK cyclin K\n", "CDKL1 cyclin dependent kinase like 1\n", "BANF1 BAF nuclear assembly factor 1\n", "BDNF brain derived neurotrophic factor\n", "BGLAP bone gamma-carboxyglutamate protein\n", "IQGAP1 IQ motif containing GTPase activating protein 1\n", "BID BH3 interacting domain death agonist\n", "BLM BLM RecQ like helicase\n", "CXCR5 C-X-C motif chemokine receptor 5\n", "CFLAR CASP8 and FADD like apoptosis regulator\n", "BMI1 BMI1 proto-oncogene, polycomb ring finger\n", "BMP2 bone morphogenetic protein 2\n", "BMP4 bone morphogenetic protein 4\n", "BMP7 bone morphogenetic protein 7\n", "KAT2B lysine acetyltransferase 2B\n", "CDK5R1 cyclin dependent kinase 5 regulatory subunit 1\n", "BOK BCL2 family apoptosis regulator BOK\n", "BRCA1 BRCA1 DNA repair associated\n", "PER2 period circadian regulator 2\n", "BRCA2 BRCA2 DNA repair associated\n", "BRDT bromodomain testis associated\n", "ZFP36L1 ZFP36 ring finger protein like 1\n", "ZFP36L2 ZFP36 ring finger protein like 2\n", "CDC123 cell division cycle 123\n", "SPHK1 sphingosine kinase 1\n", "BTC betacellulin\n", "KLF5 Kruppel like factor 5\n", "CDC16 cell division cycle 16\n", "ZPR1 ZPR1 zinc finger\n", "NAE1 NEDD8 activating enzyme E1 subunit 1\n", "BTG1 BTG anti-proliferation factor 1\n", "ANGEL2 angel homolog 2\n", "BUB1 BUB1 mitotic checkpoint serine/threonine kinase\n", "BUB1B BUB1 mitotic checkpoint serine/threonine kinase B\n", "WRAP73 WD repeat containing, antisense to TP73\n", "CCNA1 cyclin A1\n", "TIMELESS timeless circadian regulator\n", "OSGIN2 oxidative stress induced growth inhibitor family member 2\n", "EME2 essential meiotic structure-specific endonuclease subunit 2\n", "PHOX2B paired like homeobox 2B\n", "UHRF2 ubiquitin like with PHD and ring finger domains 2\n", "CDK5R2 cyclin dependent kinase 5 regulatory subunit 2\n", "BTRC beta-transducin repeat containing E3 ubiquitin protein ligase\n", "PTTG1IP PTTG1 interacting protein\n", "SENP5 SUMO specific peptidase 5\n", "USP17L2 ubiquitin specific peptidase 17 like family member 2\n", "NUDT16 nudix hydrolase 16\n", "CALM1 calmodulin 1\n", "CALM2 calmodulin 2\n", "CDKL2 cyclin dependent kinase like 2\n", "CALM3 calmodulin 3\n", "CALR calreticulin\n", "CAMK2A calcium/calmodulin dependent protein kinase II alpha\n", "CAPN2 calpain 2\n", "CAPN3 calpain 3\n", "BRSK2 BR serine/threonine kinase 2\n", "RNF8 ring finger protein 8\n", "CASP1 caspase 1\n", "CASP2 caspase 2\n", "HIP1R huntingtin interacting protein 1 related\n", "CASP4 caspase 4\n", "CASP5 caspase 5\n", "CASP3 caspase 3\n", "TM4SF5 transmembrane 4 L six family member 5\n", "CASP8 caspase 8\n", "CASP9 caspase 9\n", "CASP10 caspase 10\n", "WBP2NL WBP2 N-terminal like\n", "WHAMM WASP homolog associated with actin, golgi membranes and microtubules\n", "CTDSP1 CTD small phosphatase 1\n", "UBA3 ubiquitin like modifier activating enzyme 3\n", "CAV2 caveolin 2\n", "CAV3 caveolin 3\n", "PRC1 protein regulator of cytokinesis 1\n", "RUNX3 RUNX family transcription factor 3\n", "CCK cholecystokinin\n", "DIRAS3 DIRAS family GTPase 3\n", "CCNA2 cyclin A2\n", "CCNB1 cyclin B1\n", "CCNC cyclin C\n", "CCND2 cyclin D2\n", "PKMYT1 protein kinase, membrane associated tyrosine/threonine 1\n", "CCND3 cyclin D3\n", "CCNE1 cyclin E1\n", "CCNF cyclin F\n", "CCNG1 cyclin G1\n", "CCNG2 cyclin G2\n", "CCNH cyclin H\n", "UNC119 unc-119 lipid binding chaperone\n", "CCNT1 cyclin T1\n", "CCNT2 cyclin T2\n", "DNAJA3 DnaJ heat shock protein family (Hsp40) member A3\n", "USP2 ubiquitin specific peptidase 2\n", "USP10 ubiquitin specific peptidase 10\n", "USP8 ubiquitin specific peptidase 8\n", "LATS1 large tumor suppressor kinase 1\n", "MS4A3 membrane spanning 4-domains A3\n", "CNOT9 CCR4-NOT transcription complex subunit 9\n", "SMC3 structural maintenance of chromosomes 3\n", "AIFM1 apoptosis inducing factor mitochondria associated 1\n", "CD28 CD28 molecule\n", "CCNB2 cyclin B2\n", "CCNE2 cyclin E2\n", "CTDP1 CTD phosphatase subunit 1\n", "CD44 CD44 molecule (Indian blood group)\n", "CD53 CD53 molecule\n", "EXO1 exonuclease 1\n", "CD74 CD74 molecule\n", "CDK1 cyclin dependent kinase 1\n", "CDK11B cyclin dependent kinase 11B\n", "CDC5L cell division cycle 5 like\n", "ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2\n", "CDC6 cell division cycle 6\n", "ZW10 zw10 kinetochore protein\n", "CDC20 cell division cycle 20\n", "CDC25A cell division cycle 25A\n", "CDC25B cell division cycle 25B\n", "CDC25C cell division cycle 25C\n", "CDC27 cell division cycle 27\n", "BUB3 BUB3 mitotic checkpoint protein\n", "CDC34 cell division cycle 34, ubiqiutin conjugating enzyme\n", "CDC42 cell division cycle 42\n", "DCUN1D3 defective in cullin neddylation 1 domain containing 3\n", "CDH13 cadherin 13\n", "CDK2 cyclin dependent kinase 2\n", "CDK3 cyclin dependent kinase 3\n", "CDK4 cyclin dependent kinase 4\n", "CDK5 cyclin dependent kinase 5\n", "AURKB aurora kinase B\n", "CDK7 cyclin dependent kinase 7\n", "CDK6 cyclin dependent kinase 6\n", "PHF13 PHD finger protein 13\n", "CDK9 cyclin dependent kinase 9\n", "CDKN1A cyclin dependent kinase inhibitor 1A\n", "CDKN1B cyclin dependent kinase inhibitor 1B\n", "CDKN1C cyclin dependent kinase inhibitor 1C\n", "CDKN2A cyclin dependent kinase inhibitor 2A\n", "CDKN2B cyclin dependent kinase inhibitor 2B\n", "CDKN2C cyclin dependent kinase inhibitor 2C\n", "CDKN2D cyclin dependent kinase inhibitor 2D\n", "CDKN3 cyclin dependent kinase inhibitor 3\n", "NOLC1 nucleolar and coiled-body phosphoprotein 1\n", "TMEM67 transmembrane protein 67\n", "PTTG1 PTTG1 regulator of sister chromatid separation, securin\n", "CCPG1 cell cycle progression 1\n", "TBRG4 transforming growth factor beta regulator 4\n", "CEACAM5 CEA cell adhesion molecule 5\n", "CEBPA CCAAT enhancer binding protein alpha\n", "CENPA centromere protein A\n", "CENPC centromere protein C\n", "CENPE centromere protein E\n", "CENPF centromere protein F\n", "CETN1 centrin 1\n", "CETN2 centrin 2\n", "CETN3 centrin 3\n", "CFL1 cofilin 1\n", "PIWIL1 piwi like RNA-mediated gene silencing 1\n", "RCC1 regulator of chromosome condensation 1\n", "CHD3 chromodomain helicase DNA binding protein 3\n", "CHEK1 checkpoint kinase 1\n", "FOXN3 forkhead box N3\n", "KLF4 Kruppel like factor 4\n", "TRIP13 thyroid hormone receptor interactor 13\n", "RHOU ras homolog family member U\n", "NLRC4 NLR family CARD domain containing 4\n", "CNOT8 CCR4-NOT transcription complex subunit 8\n", "RPRD1B regulation of nuclear pre-mRNA domain containing 1B\n", "TAOK2 TAO kinase 2\n", "RPL23 ribosomal protein L23\n", "BOD1 biorientation of chromosomes in cell division 1\n", "CKS1B CDC28 protein kinase regulatory subunit 1B\n", "CKS2 CDC28 protein kinase regulatory subunit 2\n", "H1-8 H1.8 linker histone\n", "SLC9A3R1 SLC9A3 regulator 1\n", "KIF3B kinesin family member 3B\n", "WIZ WIZ zinc finger\n", "RRAGD Ras related GTP binding D\n", "CLIC1 chloride intracellular channel 1\n", "SUN2 Sad1 and UNC84 domain containing 2\n", "RECQL5 RecQ like helicase 5\n", "CLTA clathrin light chain A\n", "RAD54B RAD54 homolog B\n", "CLTC clathrin heavy chain\n", "FBXO7 F-box protein 7\n", "EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3\n", "NIPBL NIPBL cohesin loading factor\n", "PLK3 polo like kinase 3\n", "HOMER1 homer scaffold protein 1\n", "ANAPC13 anaphase promoting complex subunit 13\n", "CATSPERZ catsper channel auxiliary subunit zeta\n", "ROCK2 Rho associated coiled-coil containing protein kinase 2\n", "COL4A3 collagen type IV alpha 3 chain\n", "ANKK1 ankyrin repeat and kinase domain containing 1\n", "PSMF1 proteasome inhibitor subunit 1\n", "KIF23 kinesin family member 23\n", "POC1A POC1 centriolar protein A\n", "ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1\n", "INTS7 integrator complex subunit 7\n", "GDF15 growth differentiation factor 15\n", "MAP3K8 mitogen-activated protein kinase kinase kinase 8\n", "CNOT10 CCR4-NOT transcription complex subunit 10\n", "EEF1E1 eukaryotic translation elongation factor 1 epsilon 1\n", "ANAPC15 anaphase promoting complex subunit 15\n", "AHCTF1 AT-hook containing transcription factor 1\n", "VPS4B vacuolar protein sorting 4 homolog B\n", "RTTN rotatin\n", "RMI2 RecQ mediated genome instability 2\n", "NEK7 NIMA related kinase 7\n", "NOX4 NADPH oxidase 4\n", "SYCP3 synaptonemal complex protein 3\n", "NSL1 NSL1 component of MIS12 kinetochore complex\n", "MACROH2A1 macroH2A.1 histone\n", "SIN3A SIN3 transcription regulator family member A\n", "ZNF385A zinc finger protein 385A\n", "EPGN epithelial mitogen\n", "SYF2 SYF2 pre-mRNA splicing factor\n", "KANK2 KN motif and ankyrin repeat domains 2\n", "CLOCK clock circadian regulator\n", "BABAM2 BRISC and BRCA1 A complex member 2\n", "ATF2 activating transcription factor 2\n", "CREBL2 cAMP responsive element binding protein like 2\n", "KIF20B kinesin family member 20B\n", "SH2B1 SH2B adaptor protein 1\n", "MAD2L1BP MAD2L1 binding protein\n", "WTAP WT1 associated protein\n", "CHMP2B charged multivesicular body protein 2B\n", "CRY1 cryptochrome circadian regulator 1\n", "HINFP histone H4 transcription factor\n", "ULK3 unc-51 like kinase 3\n", "RNF167 ring finger protein 167\n", "CTCFL CCCTC-binding factor like\n", "MAPK14 mitogen-activated protein kinase 14\n", "L3MBTL1 L3MBTL histone methyl-lysine binding protein 1\n", "FAM32A family with sequence similarity 32 member A\n", "ARHGEF10 Rho guanine nucleotide exchange factor 10\n", "KLHDC3 kelch domain containing 3\n", "CSNK1A1 casein kinase 1 alpha 1\n", "CSNK1D casein kinase 1 delta\n", "CSNK1E casein kinase 1 epsilon\n", "CSNK2A1 casein kinase 2 alpha 1\n", "CSNK2A2 casein kinase 2 alpha 2\n", "MDC1 mediator of DNA damage checkpoint 1\n", "CEP135 centrosomal protein 135\n", "CUZD1 CUB and zona pellucida like domains 1\n", "MARF1 meiosis regulator and mRNA stability factor 1\n", "SENP6 SUMO specific peptidase 6\n", "ANKRD17 ankyrin repeat domain 17\n", "GIGYF2 GRB10 interacting GYF protein 2\n", "NKX2-5 NK2 homeobox 5\n", "APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1\n", "CTBP1 C-terminal binding protein 1\n", "CCN2 cellular communication network factor 2\n", "ZNF830 zinc finger protein 830\n", "SLFN11 schlafen family member 11\n", "POLDIP2 DNA polymerase delta interacting protein 2\n", "CTNNB1 catenin beta 1\n", "CROCC ciliary rootlet coiled-coil, rootletin\n", "PUM1 pumilio RNA binding family member 1\n", "ESPL1 extra spindle pole bodies like 1, separase\n", "CEP57 centrosomal protein 57\n", "CTSH cathepsin H\n", "UTP14C UTP14C small subunit processome component\n", "TDRD12 tudor domain containing 12\n", "RAB11FIP3 RAB11 family interacting protein 3\n", "CCDC69 coiled-coil domain containing 69\n", "CYLD CYLD lysine 63 deubiquitinase\n", "CDCA3 cell division cycle associated 3\n", "HDAC9 histone deacetylase 9\n", "KNTC1 kinetochore associated 1\n", "CYP1A1 cytochrome P450 family 1 subfamily A member 1\n", "CCP110 centriolar coiled-coil protein 110\n", "NLRP12 NLR family pyrin domain containing 12\n", "ZFP42 ZFP42 zinc finger protein\n", "RIPOR2 RHO family interacting cell polarization regulator 2\n", "ROMO1 reactive oxygen species modulator 1\n", "HDAC4 histone deacetylase 4\n", "PCLAF PCNA clamp associated factor\n", "RASSF2 Ras association domain family member 2\n", "MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein\n", "LIN54 lin-54 DREAM MuvB core complex component\n", "CYP27B1 cytochrome P450 family 27 subfamily B member 1\n", "DLGAP5 DLG associated protein 5\n", "CKAP5 cytoskeleton associated protein 5\n", "DACH1 dachshund family transcription factor 1\n", "MAML1 mastermind like transcriptional coactivator 1\n", "DAP death associated protein\n", "OR1A2 olfactory receptor family 1 subfamily A member 2\n", "DAPK3 death associated protein kinase 3\n", "DAZL deleted in azoospermia like\n", "BRINP1 BMP/retinoic acid inducible neural specific 1\n", "NUF2 NUF2 component of NDC80 kinetochore complex\n", "SFI1 SFI1 centrin binding protein\n", "CUL7 cullin 7\n", "RB1CC1 RB1 inducible coiled-coil 1\n", "SPAG8 sperm associated antigen 8\n", "LIN52 lin-52 DREAM MuvB core complex component\n", "DCTN1 dynactin subunit 1\n", "MELK maternal embryonic leucine zipper kinase\n", "NEK9 NIMA related kinase 9\n", "DDB1 damage specific DNA binding protein 1\n", "GINS1 GINS complex subunit 1\n", "GADD45A growth arrest and DNA damage inducible alpha\n", "FBXL3 F-box and leucine rich repeat protein 3\n", "DDIT3 DNA damage inducible transcript 3\n", "PHGDH phosphoglycerate dehydrogenase\n", "MYEF2 myelin expression factor 2\n", "DDX3X DEAD-box helicase 3 X-linked\n", "DDX5 DEAD-box helicase 5\n", "CABLES1 Cdk5 and Abl enzyme substrate 1\n", "KIAA0753 KIAA0753\n", "DDX11 DEAD/H-box helicase 11\n", "CDCA2 cell division cycle associated 2\n", "PSMD6 proteasome 26S subunit, non-ATPase 6\n", "CHMP7 charged multivesicular body protein 7\n", "MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2\n", "SLC26A8 solute carrier family 26 member 8\n", "TLK1 tousled like kinase 1\n", "TAS2R13 taste 2 receptor member 13\n", "FBXO22 F-box protein 22\n", "FBXO6 F-box protein 6\n", "FBXO5 F-box protein 5\n", "FBXO4 F-box protein 4\n", "PARD6A par-6 family cell polarity regulator alpha\n", "WASHC5 WASH complex subunit 5\n", "KLHL21 kelch like family member 21\n", "ANKRD2 ankyrin repeat domain 2\n", "DHCR24 24-dehydrocholesterol reductase\n", "DHFR dihydrofolate reductase\n", "NCAPD2 non-SMC condensin I complex subunit D2\n", "KIF14 kinesin family member 14\n", "DLG1 discs large MAGUK scaffold protein 1\n", "DCLRE1A DNA cross-link repair 1A\n", "SESN2 sestrin 2\n", "DMPK DM1 protein kinase\n", "DMRT1 doublesex and mab-3 related transcription factor 1\n", "DNA2 DNA replication helicase/nuclease 2\n", "USP3 ubiquitin specific peptidase 3\n", "TNFSF15 TNF superfamily member 15\n", "RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1\n", "DYNC1H1 dynein cytoplasmic 1 heavy chain 1\n", "FAM162A family with sequence similarity 162 member A\n", "DYNC1I2 dynein cytoplasmic 1 intermediate chain 2\n", "DNM2 dynamin 2\n", "RBX1 ring-box 1\n", "DNMT3A DNA methyltransferase 3 alpha\n", "THOC1 THO complex 1\n", "REC8 REC8 meiotic recombination protein\n", "DMTF1 cyclin D binding myb like transcription factor 1\n", "CASP8AP2 caspase 8 associated protein 2\n", "DRD2 dopamine receptor D2\n", "DRD3 dopamine receptor D3\n", "ARID3A AT-rich interaction domain 3A\n", "MARVELD1 MARVEL domain containing 1\n", "HDAC5 histone deacetylase 5\n", "PDCD6 programmed cell death 6\n", "BCL2L10 BCL2 like 10\n", "BCL2L11 BCL2 like 11\n", "RCAN1 regulator of calcineurin 1\n", "PDCD6IP programmed cell death 6 interacting protein\n", "L3MBTL2 L3MBTL histone methyl-lysine binding protein 2\n", "DUSP1 dual specificity phosphatase 1\n", "CHAF1A chromatin assembly factor 1 subunit A\n", "DUSP3 dual specificity phosphatase 3\n", "PARP3 poly(ADP-ribose) polymerase family member 3\n", "TOM1L1 target of myb1 like 1 membrane trafficking protein\n", "DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A\n", "SMC4 structural maintenance of chromosomes 4\n", "E2F1 E2F transcription factor 1\n", "E2F2 E2F transcription factor 2\n", "E2F3 E2F transcription factor 3\n", "E2F4 E2F transcription factor 4\n", "E2F5 E2F transcription factor 5\n", "E2F6 E2F transcription factor 6\n", "E4F1 E4F transcription factor 1\n", "CCNQ cyclin Q\n", "USH1C USH1 protein network component harmonin\n", "ECT2 epithelial cell transforming 2\n", "NUPR1 nuclear protein 1, transcriptional regulator\n", "GMNN geminin DNA replication inhibitor\n", "ACTR3 actin related protein 3\n", "ACTR2 actin related protein 2\n", "EDN1 endothelin 1\n", "EDN3 endothelin 3\n", "HEXIM2 HEXIM P-TEFb complex subunit 2\n", "PHC1 polyhomeotic homolog 1\n", "RPS27L ribosomal protein S27 like\n", "CTDSP2 CTD small phosphatase 2\n", "RAD50 RAD50 double strand break repair protein\n", "KIF20A kinesin family member 20A\n", "ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2\n", "USP26 ubiquitin specific peptidase 26\n", "FEM1B fem-1 homolog B\n", "ACTR1B actin related protein 1B\n", "ACTR1A actin related protein 1A\n", "SETDB2 SET domain bifurcated histone lysine methyltransferase 2\n", "MLXIPL MLX interacting protein like\n", "CNTD1 cyclin N-terminal domain containing 1\n", "OPTN optineurin\n", "YAF2 YY1 associated factor 2\n", "SH3GLB1 SH3 domain containing GRB2 like, endophilin B1\n", "LATS2 large tumor suppressor kinase 2\n", "AKAP9 A-kinase anchoring protein 9\n", "EGF epidermal growth factor\n", "HMCN1 hemicentin 1\n", "TBC1D10A TBC1 domain family member 10A\n", "EGFR epidermal growth factor receptor\n", "SBDS SBDS ribosome maturation factor\n", "CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1\n", "EIF4E eukaryotic translation initiation factor 4E\n", "EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1\n", "EIF4G1 eukaryotic translation initiation factor 4 gamma 1\n", "EIF4G2 eukaryotic translation initiation factor 4 gamma 2\n", "HASPIN histone H3 associated protein kinase\n", "RBM7 RNA binding motif protein 7\n", "DYNC1LI1 dynein cytoplasmic 1 light intermediate chain 1\n", "ING4 inhibitor of growth family member 4\n", "MRNIP MRN complex interacting protein\n", "AATF apoptosis antagonizing transcription factor\n", "SENP2 SUMO specific peptidase 2\n", "PSME3 proteasome activator subunit 3\n", "NME6 NME/NM23 nucleoside diphosphate kinase 6\n", "EMD emerin\n", "EML1 EMAP like 1\n", "CKAP2 cytoskeleton associated protein 2\n", "RASSF4 Ras association domain family member 4\n", "TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase\n", "FLOT1 flotillin 1\n", "PSMD14 proteasome 26S subunit, non-ATPase 14\n", "TUBD1 tubulin delta 1\n", "TUBE1 tubulin epsilon 1\n", "ENG endoglin\n", "CTDSPL CTD small phosphatase like\n", "ENSA endosulfine alpha\n", "EP300 E1A binding protein p300\n", "EPB41 erythrocyte membrane protein band 4.1\n", "EPB41L2 erythrocyte membrane protein band 4.1 like 2\n", "HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5\n", "NIN ninein\n", "NUSAP1 nucleolar and spindle associated protein 1\n", "ANKRD31 ankyrin repeat domain 31\n", "DUSP13 dual specificity phosphatase 13\n", "RIDA reactive intermediate imine deaminase A homolog\n", "EPS8 epidermal growth factor receptor pathway substrate 8\n", "SPRY1 sprouty RTK signaling antagonist 1\n", "SPRY2 sprouty RTK signaling antagonist 2\n", "ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit\n", "CCDC8 coiled-coil domain containing 8\n", "EREG epiregulin\n", "BRIP1 BRCA1 interacting protein C-terminal helicase 1\n", "CDK2AP2 cyclin dependent kinase 2 associated protein 2\n", "ERCC4 ERCC excision repair 4, endonuclease catalytic subunit\n", "ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit\n", "ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit\n", "ERCC6 ERCC excision repair 6, chromatin remodeling factor\n", "ZMPSTE24 zinc metallopeptidase STE24\n", "AKAP8 A-kinase anchoring protein 8\n", "ERH ERH mRNA splicing and mitosis factor\n", "ERF ETS2 repressor factor\n", "CENPW centromere protein W\n", "STAG1 stromal antigen 1\n", "ERN1 endoplasmic reticulum to nucleus signaling 1\n", "SHISA5 shisa family member 5\n", "ESRRB estrogen related receptor beta\n", "MAEA macrophage erythroblast attacher, E3 ubiquitin ligase\n", "PAK4 p21 (RAC1) activated kinase 4\n", "KATNB1 katanin regulatory subunit B1\n", "CDKL3 cyclin dependent kinase like 3\n", "CCNO cyclin O\n", "TFDP3 transcription factor Dp family member 3\n", "MECOM MDS1 and EVI1 complex locus\n", "EVI2B ecotropic viral integration site 2B\n", "IKZF1 IKAROS family zinc finger 1\n", "MCMDC2 minichromosome maintenance domain containing 2\n", "KLHL41 kelch like family member 41\n", "RRAGB Ras related GTP binding B\n", "RXFP3 relaxin family peptide receptor 3\n", "MND1 meiotic nuclear divisions 1\n", "EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit\n", "F2R coagulation factor II thrombin receptor\n", "HORMAD1 HORMA domain containing 1\n", "CNTROB centrobin, centriole duplication and spindle assembly protein\n", "F3 coagulation factor III, tissue factor\n", "RAB6C RAB6C, member RAS oncogene family\n", "NPM2 nucleophosmin/nucleoplasmin 2\n", "HMG20B high mobility group 20B\n", "WAC WW domain containing adaptor with coiled-coil\n", "PYHIN1 pyrin and HIN domain family member 1\n", "SYCE2 synaptonemal complex central element protein 2\n", "FANCA FA complementation group A\n", "FANCD2 FA complementation group D2\n", "CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2\n", "USP44 ubiquitin specific peptidase 44\n", "TUBA1B tubulin alpha 1b\n", "DACT1 dishevelled binding antagonist of beta catenin 1\n", "PCGF6 polycomb group ring finger 6\n", "TUBB3 tubulin beta 3 class III\n", "TUBB4A tubulin beta 4A class IVa\n", "FZR1 fizzy and cell division cycle 20 related 1\n", "SCGB3A1 secretoglobin family 3A member 1\n", "TUBB4B tubulin beta 4B class IVb\n", "BTN2A2 butyrophilin subfamily 2 member A2\n", "FAP fibroblast activation protein alpha\n", "SYCP2 synaptonemal complex protein 2\n", "TAOK3 TAO kinase 3\n", "NOD1 nucleotide binding oligomerization domain containing 1\n", "ANAPC10 anaphase promoting complex subunit 10\n", "DLC1 DLC1 Rho GTPase activating protein\n", "NDRG1 N-myc downstream regulated 1\n", "ATRIP ATR interacting protein\n", "RACK1 receptor for activated C kinase 1\n", "NDC80 NDC80 kinetochore complex component\n", "CEP78 centrosomal protein 78\n", "ABRAXAS1 abraxas 1, BRCA1 A complex subunit\n", "STRADA STE20 related adaptor alpha\n", "DUX4 double homeobox 4\n", "CRLF3 cytokine receptor like factor 3\n", "PRMT5 protein arginine methyltransferase 5\n", "WNT16 Wnt family member 16\n", "TUBGCP3 tubulin gamma complex associated protein 3\n", "FEN1 flap structure-specific endonuclease 1\n", "RWDD1 RWD domain containing 1\n", "RBM14 RNA binding motif protein 14\n", "FER FER tyrosine kinase\n", "FES FES proto-oncogene, tyrosine kinase\n", "PPME1 protein phosphatase methylesterase 1\n", "FGF8 fibroblast growth factor 8\n", "FGF10 fibroblast growth factor 10\n", "FGFR1 fibroblast growth factor receptor 1\n", "FGFR2 fibroblast growth factor receptor 2\n", "GPNMB glycoprotein nmb\n", "MAD2L2 mitotic arrest deficient 2 like 2\n", "TACC3 transforming acidic coiled-coil containing protein 3\n", "PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2\n", "PIBF1 progesterone immunomodulatory binding factor 1\n", "FHL1 four and a half LIM domains 1\n", "FHIT fragile histidine triad diadenosine triphosphatase\n", "SNX9 sorting nexin 9\n", "ANAPC5 anaphase promoting complex subunit 5\n", "ANAPC7 anaphase promoting complex subunit 7\n", "TADA3 transcriptional adaptor 3\n", "YTHDF2 YTH N6-methyladenosine RNA binding protein 2\n", "FOXG1 forkhead box G1\n", "FOXC1 forkhead box C1\n", "ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1\n", "LCMT1 leucine carboxyl methyltransferase 1\n", "FOXE3 forkhead box E3\n", "FOXM1 forkhead box M1\n", "CARM1 coactivator associated arginine methyltransferase 1\n", "CHMP4C charged multivesicular body protein 4C\n", "TRIM72 tripartite motif containing 72\n", "FLNA filamin A\n", "MYBBP1A MYB binding protein 1a\n", "FLT3LG fms related receptor tyrosine kinase 3 ligand\n", "CIB1 calcium and integrin binding 1\n", "SLF1 SMC5-SMC6 complex localization factor 1\n", "KAT5 lysine acetyltransferase 5\n", "IPO7 importin 7\n", "SPOUT1 SPOUT domain containing methyltransferase 1\n", "ZNRD2 zinc ribbon domain containing 2\n", "UBD ubiquitin D\n", "BATF basic leucine zipper ATF-like transcription factor\n", "TRIAP1 TP53 regulated inhibitor of apoptosis 1\n", "DCTN2 dynactin subunit 2\n", "ANP32B acidic nuclear phosphoprotein 32 family member B\n", "LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5\n", "RTF2 replication termination factor 2\n", "SLC25A33 solute carrier family 25 member 33\n", "CHMP5 charged multivesicular body protein 5\n", "GTSE1 G2 and S-phase expressed 1\n", "DTL denticleless E3 ubiquitin protein ligase homolog\n", "ANAPC11 anaphase promoting complex subunit 11\n", "ZC3HC1 zinc finger C3HC-type containing 1\n", "HBP1 HMG-box transcription factor 1\n", "PDCD2L programmed cell death 2 like\n", "TACC2 transforming acidic coiled-coil containing protein 2\n", "SIRT7 sirtuin 7\n", "CHORDC1 cysteine and histidine rich domain containing 1\n", "CINP cyclin dependent kinase 2 interacting protein\n", "SMC2 structural maintenance of chromosomes 2\n", "ERN2 endoplasmic reticulum to nucleus signaling 2\n", "USP16 ubiquitin specific peptidase 16\n", "AKAP8L A-kinase anchoring protein 8 like\n", "P3H4 prolyl 3-hydroxylase family member 4 (inactive)\n", "HEXIM1 HEXIM P-TEFb complex subunit 1\n", "SPAG5 sperm associated antigen 5\n", "CYFIP2 cytoplasmic FMR1 interacting protein 2\n", "STAMBP STAM binding protein\n", "TXNIP thioredoxin interacting protein\n", "CNPPD1 cyclin Pas1/PHO80 domain containing 1\n", "BEX3 brain expressed X-linked 3\n", "GAS2L1 growth arrest specific 2 like 1\n", "RGS14 regulator of G protein signaling 14\n", "MLH3 mutL homolog 3\n", "KHDRBS1 KH RNA binding domain containing, signal transduction associated 1\n", "SND1 staphylococcal nuclease and tudor domain containing 1\n", "CTCF CCCTC-binding factor\n", "MTOR mechanistic target of rapamycin kinase\n", "CGRRF1 cell growth regulator with ring finger domain 1\n", "CGREF1 cell growth regulator with EF-hand domain 1\n", "RRAGA Ras related GTP binding A\n", "ANKRD1 ankyrin repeat domain 1\n", "SSX2IP SSX family member 2 interacting protein\n", "NR5A2 nuclear receptor subfamily 5 group A member 2\n", "ECRG4 ECRG4 augurin precursor\n", "CHMP3 charged multivesicular body protein 3\n", "CDK5RAP1 CDK5 regulatory subunit associated protein 1\n", "MRGPRX2 MAS related GPR family member X2\n", "MTBP MDM2 binding protein\n", "NR5A1 nuclear receptor subfamily 5 group A member 1\n", "RAB11FIP4 RAB11 family interacting protein 4\n", "USP39 ubiquitin specific peptidase 39\n", "POLD3 DNA polymerase delta 3, accessory subunit\n", "DOT1L DOT1 like histone lysine methyltransferase\n", "LZTS2 leucine zipper tumor suppressor 2\n", "BRSK1 BR serine/threonine kinase 1\n", "NFAT5 nuclear factor of activated T cells 5\n", "NUDC nuclear distribution C, dynein complex regulator\n", "BBC3 BCL2 binding component 3\n", "PLK4 polo like kinase 4\n", "STAG3 stromal antigen 3\n", "STAG2 stromal antigen 2\n", "HECA hdc homolog, cell cycle regulator\n", "SLX4 SLX4 structure-specific endonuclease subunit\n", "SMC1B structural maintenance of chromosomes 1B\n", "PTTG2 pituitary tumor-transforming 2\n", "KCNH5 potassium voltage-gated channel subfamily H member 5\n", "GIPC1 GIPC PDZ domain containing family member 1\n", "CIDEB cell death inducing DFFA like effector b\n", "CAB39 calcium binding protein 39\n", "UIMC1 ubiquitin interaction motif containing 1\n", "NES nestin\n", "PLK2 polo like kinase 2\n", "ZMYND11 zinc finger MYND-type containing 11\n", "GAK cyclin G associated kinase\n", "SPIRE2 spire type actin nucleation factor 2\n", "ARPP19 cAMP regulated phosphoprotein 19\n", "WWOX WW domain containing oxidoreductase\n", "NEK6 NIMA related kinase 6\n", "MCM8 minichromosome maintenance 8 homologous recombination repair factor\n", "RTEL1 regulator of telomere elongation helicase 1\n", "TUBG2 tubulin gamma 2\n", "TMEM8B transmembrane protein 8B\n", "ZNF268 zinc finger protein 268\n", "CDK12 cyclin dependent kinase 12\n", "VPS4A vacuolar protein sorting 4 homolog A\n", "STRA8 stimulated by retinoic acid 8\n", "SDCCAG8 SHH signaling and ciliogenesis regulator SDCCAG8\n", "ENTR1 endosome associated trafficking regulator 1\n", "GAS1 growth arrest specific 1\n", "GAS2 growth arrest specific 2\n", "GAS6 growth arrest specific 6\n", "MAP3K20 mitogen-activated protein kinase kinase kinase 20\n", "GATA3 GATA binding protein 3\n", "DNER delta/notch like EGF repeat containing\n", "GATA6 GATA binding protein 6\n", "PARD6G par-6 family cell polarity regulator gamma\n", "SIK1 salt inducible kinase 1\n", "KAT2A lysine acetyltransferase 2A\n", "SIX4 SIX homeobox 4\n", "TUBGCP2 tubulin gamma complex associated protein 2\n", "TUBGCP4 tubulin gamma complex associated protein 4\n", "OPN1MW opsin 1, medium wave sensitive\n", "TUBA8 tubulin alpha 8\n", "LILRB1 leukocyte immunoglobulin like receptor B1\n", "CHMP2A charged multivesicular body protein 2A\n", "GEM GTP binding protein overexpressed in skeletal muscle\n", "C10orf99 chromosome 10 open reading frame 99\n", "GFI1 growth factor independent 1 transcriptional repressor\n", "PDCD4 programmed cell death 4\n", "JMY junction mediating and regulatory protein, p53 cofactor\n", "USP19 ubiquitin specific peptidase 19\n", "PARD6B par-6 family cell polarity regulator beta\n", "GJA1 gap junction protein alpha 1\n", "TUBB6 tubulin beta 6 class V\n", "JTB jumping translocation breakpoint\n", "TTBK1 tau tubulin kinase 1\n", "BLCAP BLCAP apoptosis inducing factor\n", "AFAP1L2 actin filament associated protein 1 like 2\n", "TXNL4A thioredoxin like 4A\n", "SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone\n", "GADD45G growth arrest and DNA damage inducible gamma\n", "APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2\n", "EHMT2 euchromatic histone lysine methyltransferase 2\n", "DBF4 DBF4 zinc finger\n", "SPIN1 spindlin 1\n", "GLI1 GLI family zinc finger 1\n", "EHD1 EH domain containing 1\n", "SPDYC speedy/RINGO cell cycle regulator family member C\n", "RPS6KA6 ribosomal protein S6 kinase A6\n", "BTG3 BTG anti-proliferation factor 3\n", "UBE2S ubiquitin conjugating enzyme E2 S\n", "PRPF19 pre-mRNA processing factor 19\n", "INSM2 INSM transcriptional repressor 2\n", "GML glycosylphosphatidylinositol anchored molecule like\n", "PPP1R9B protein phosphatase 1 regulatory subunit 9B\n", "GNAI1 G protein subunit alpha i1\n", "GNAI2 G protein subunit alpha i2\n", "SPATA22 spermatogenesis associated 22\n", "GNAI3 G protein subunit alpha i3\n", "SGSM3 small G protein signaling modulator 3\n", "BEX2 brain expressed X-linked 2\n", "CCNI cyclin I\n", "COPS5 COP9 signalosome subunit 5\n", "GOLGA2 golgin A2\n", "PSRC1 proline and serine rich coiled-coil 1\n", "SFN stratifin\n", "KIF2C kinesin family member 2C\n", "TLK2 tousled like kinase 2\n", "HORMAD2 HORMA domain containing 2\n", "GPR3 G protein-coupled receptor 3\n", "RAB35 RAB35, member RAS oncogene family\n", "TDRKH tudor and KH domain containing\n", "PIM2 Pim-2 proto-oncogene, serine/threonine kinase\n", "GPER1 G protein-coupled estrogen receptor 1\n", "HTRA2 HtrA serine peptidase 2\n", "TENT4A terminal nucleotidyltransferase 4A\n", "EML4 EMAP like 4\n", "KMT5A lysine methyltransferase 5A\n", "TUBA1C tubulin alpha 1c\n", "GRK5 G protein-coupled receptor kinase 5\n", "CNTRL centriolin\n", "UBE2C ubiquitin conjugating enzyme E2 C\n", "GPX1 glutathione peroxidase 1\n", "TOPBP1 DNA topoisomerase II binding protein 1\n", "TRIOBP TRIO and F-actin binding protein\n", "PLPP7 phospholipid phosphatase 7 (inactive)\n", "PARD3B par-3 family cell polarity regulator beta\n", "TMEM119 transmembrane protein 119\n", "GRIN2A glutamate ionotropic receptor NMDA type subunit 2A\n", "NR3C1 nuclear receptor subfamily 3 group C member 1\n", "MEI1 meiotic double-stranded break formation protein 1\n", "KATNA1 katanin catalytic subunit A1\n", "PRDM7 PR/SET domain 7\n", "PRDM5 PR/SET domain 5\n", "CIT citron rho-interacting serine/threonine kinase\n", "CEP43 centrosomal protein 43\n", "GSPT1 G1 to S phase transition 1\n", "KIF3A kinesin family member 3A\n", "ZWINT ZW10 interacting kinetochore protein\n", "ZNF503 zinc finger protein 503\n", "KLHL22 kelch like family member 22\n", "CDC37 cell division cycle 37, HSP90 cochaperone\n", "DMC1 DNA meiotic recombinase 1\n", "PLAAT3 phospholipase A and acyltransferase 3\n", "ZBTB49 zinc finger and BTB domain containing 49\n", "SULT1A4 sulfotransferase family 1A member 4\n", "GTF2H1 general transcription factor IIH subunit 1\n", "NUDT6 nudix hydrolase 6\n", "WDHD1 WD repeat and HMG-box DNA binding protein 1\n", "FAM107A family with sequence similarity 107 member A\n", "TBRG1 transforming growth factor beta regulator 1\n", "LZTS1 leucine zipper tumor suppressor 1\n", "WDR6 WD repeat domain 6\n", "RASSF1 Ras association domain family member 1\n", "CEP250 centrosomal protein 250\n", "CHEK2 checkpoint kinase 2\n", "TTL tubulin tyrosine ligase\n", "MASTL microtubule associated serine/threonine kinase like\n", "H2AX H2A.X variant histone\n", "ZFYVE19 zinc finger FYVE-type containing 19\n", "MAEL maelstrom spermatogenic transposon silencer\n", "AVPI1 arginine vasopressin induced 1\n", "WEE2 WEE2 oocyte meiosis inhibiting kinase\n", "AJUBA ajuba LIM protein\n", "LSM10 LSM10, U7 small nuclear RNA associated\n", "PMF1 polyamine modulated factor 1\n", "HCFC1 host cell factor C1\n", "EDA2R ectodysplasin A2 receptor\n", "HTT huntingtin\n", "DCTN3 dynactin subunit 3\n", "HELLS helicase, lymphoid specific\n", "HGF hepatocyte growth factor\n", "TREX1 three prime repair exonuclease 1\n", "HHEX hematopoietically expressed homeobox\n", "NANOGP8 Nanog homeobox retrogene P8\n", "HIC1 HIC ZBTB transcriptional repressor 1\n", "HIP1 huntingtin interacting protein 1\n", "HINT1 histidine triad nucleotide binding protein 1\n", "SMYD1 SET and MYND domain containing 1\n", "ECD ecdysoneless cell cycle regulator\n", "HLA-G major histocompatibility complex, class I, G\n", "PHB2 prohibitin 2\n", "TUSC2 tumor suppressor 2, mitochondrial calcium regulator\n", "CBX3 chromobox 3\n", "OIP5 Opa interacting protein 5\n", "HMGA1 high mobility group AT-hook 1\n", "HMMR hyaluronan mediated motility receptor\n", "NR4A1 nuclear receptor subfamily 4 group A member 1\n", "PPP1R10 protein phosphatase 1 regulatory subunit 10\n", "FOXA1 forkhead box A1\n", "HNRNPU heterogeneous nuclear ribonucleoprotein U\n", "HAUS8 HAUS augmin like complex subunit 8\n", "RINT1 RAD50 interactor 1\n", "USP51 ubiquitin specific peptidase 51\n", "HPGD 15-hydroxyprostaglandin dehydrogenase\n", "HRAS HRas proto-oncogene, GTPase\n", "PRMT2 protein arginine methyltransferase 2\n", "PRMT1 protein arginine methyltransferase 1\n", "HES1 hes family bHLH transcription factor 1\n", "LSM11 LSM11, U7 small nuclear RNA associated\n", "POC5 POC5 centriolar protein\n", "HSF1 heat shock transcription factor 1\n", "INCA1 inhibitor of CDK, cyclin A1 interacting protein 1\n", "HSPA1A heat shock protein family A (Hsp70) member 1A\n", "HSPA1B heat shock protein family A (Hsp70) member 1B\n", "HSPA2 heat shock protein family A (Hsp70) member 2\n", "SYCE1 synaptonemal complex central element protein 1\n", "HSP90AA1 heat shock protein 90 alpha family class A member 1\n", "HSP90AB1 heat shock protein 90 alpha family class B member 1\n" ] }, { "name": "stdout", "output_type": "stream", "text": [ "MIIP migration and invasion inhibitory protein\n", "HSPD1 heat shock protein family D (Hsp60) member 1\n", "HSPE1 heat shock protein family E (Hsp10) member 1\n", "HUS1 HUS1 checkpoint clamp component\n", "HYAL1 hyaluronidase 1\n", "ICAM1 intercellular adhesion molecule 1\n", "ID1 inhibitor of DNA binding 1, HLH protein\n", "ID2 inhibitor of DNA binding 2\n", "ID3 inhibitor of DNA binding 3, HLH protein\n", "ID4 inhibitor of DNA binding 4, HLH protein\n", "SNX33 sorting nexin 33\n", "PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2\n", "IFI16 interferon gamma inducible protein 16\n", "PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1\n", "TUBGCP6 tubulin gamma complex associated protein 6\n", "IFNG interferon gamma\n", "IFNW1 interferon omega 1\n", "MISP mitotic spindle positioning\n", "NANOS2 nanos C2HC-type zinc finger 2\n", "IGF1 insulin like growth factor 1\n", "IGF2 insulin like growth factor 2\n", "CCNB3 cyclin B3\n", "LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1\n", "TNKS1BP1 tankyrase 1 binding protein 1\n", "MYOCD myocardin\n", "CEP295 centrosomal protein 295\n", "IK IK cytokine\n", "IL1A interleukin 1 alpha\n", "IL1B interleukin 1 beta\n", "IL4R interleukin 4 receptor\n", "CXCL8 C-X-C motif chemokine ligand 8\n", "IL10 interleukin 10\n", "TRNP1 TMF1 regulated nuclear protein 1\n", "IL12A interleukin 12A\n", "IL12B interleukin 12B\n", "BRINP3 BMP/retinoic acid inducible neural specific 3\n", "ILK integrin linked kinase\n", "INCENP inner centromere protein\n", "ING1 inhibitor of growth family member 1\n", "ING2 inhibitor of growth family member 2\n", "INHA inhibin subunit alpha\n", "INHBA inhibin subunit beta A\n", "TUBB8 tubulin beta 8 class VIII\n", "CXCL10 C-X-C motif chemokine ligand 10\n", "INS insulin\n", "PLK5 polo like kinase 5 (inactive)\n", "INSM1 INSM transcriptional repressor 1\n", "INSR insulin receptor\n", "PPP2R3B protein phosphatase 2 regulatory subunit B''beta\n", "IRF1 interferon regulatory factor 1\n", "RAD21L1 RAD21 cohesin complex component like 1\n", "IRF6 interferon regulatory factor 6\n", "TUBB2B tubulin beta 2B class IIb\n", "ZNF385B zinc finger protein 385B\n", "ITGB1 integrin subunit beta 1\n", "JAK2 Janus kinase 2\n", "JUN Jun proto-oncogene, AP-1 transcription factor subunit\n", "JUNB JunB proto-oncogene, AP-1 transcription factor subunit\n", "JUND JunD proto-oncogene, AP-1 transcription factor subunit\n", "MEI4 meiotic double-stranded break formation protein 4\n", "CCNYL1 cyclin Y like 1\n", "KCNA5 potassium voltage-gated channel subfamily A member 5\n", "PPP1R1C protein phosphatase 1 regulatory inhibitor subunit 1C\n", "SGO2 shugoshin 2\n", "KEL Kell metallo-endopeptidase (Kell blood group)\n", "KIF2A kinesin family member 2A\n", "KIF11 kinesin family member 11\n", "KIFC1 kinesin family member C1\n", "KIF25 kinesin family member 25\n", "KIF22 kinesin family member 22\n", "KPNB1 karyopherin subunit beta 1\n", "IPO5 importin 5\n", "CCSAP centriole, cilia and spindle associated protein\n", "ACTR8 actin related protein 8\n", "KRT18 keratin 18\n", "C10orf90 chromosome 10 open reading frame 90\n", "STMN1 stathmin 1\n", "LCK LCK proto-oncogene, Src family tyrosine kinase\n", "LEP leptin\n", "LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase\n", "IHO1 interactor of HORMAD1 1\n", "LIF LIF interleukin 6 family cytokine\n", "LIG1 DNA ligase 1\n", "LIG3 DNA ligase 3\n", "LIG4 DNA ligase 4\n", "LIMS1 LIM zinc finger domain containing 1\n", "LMNA lamin A/C\n", "LRP6 LDL receptor related protein 6\n", "LRP5 LDL receptor related protein 5\n", "MAD2L1 mitotic arrest deficient 2 like 1\n", "SMAD3 SMAD family member 3\n", "TMPRSS11A transmembrane serine protease 11A\n", "MAGEA2 MAGE family member A2\n", "CACUL1 CDK2 associated cullin domain 1\n", "SPRED2 sprouty related EVH1 domain containing 2\n", "TP53INP1 tumor protein p53 inducible nuclear protein 1\n", "MAP4 microtubule associated protein 4\n", "MAPT microtubule associated protein tau\n", "MAX MYC associated factor X\n", "MCM2 minichromosome maintenance complex component 2\n", "MCM3 minichromosome maintenance complex component 3\n", "MCM4 minichromosome maintenance complex component 4\n", "MCM5 minichromosome maintenance complex component 5\n", "MCM6 minichromosome maintenance complex component 6\n", "MCM7 minichromosome maintenance complex component 7\n", "SKA2 spindle and kinetochore associated complex subunit 2\n", "SGO1 shugoshin 1\n", "MDM2 MDM2 proto-oncogene\n", "MDM4 MDM4 regulator of p53\n", "MECP2 methyl-CpG binding protein 2\n", "PSMA8 proteasome 20S subunit alpha 8\n", "MEF2C myocyte enhancer factor 2C\n", "MEIS2 Meis homeobox 2\n", "MEN1 menin 1\n", "AGO4 argonaute RISC component 4\n", "MIF macrophage migration inhibitory factor\n", "CXCL9 C-X-C motif chemokine ligand 9\n", "MKI67 marker of proliferation Ki-67\n", "MLF1 myeloid leukemia factor 1\n", "MLH1 mutL homolog 1\n", "FOXO4 forkhead box O4\n", "MME membrane metalloendopeptidase\n", "MMP14 matrix metallopeptidase 14\n", "MNAT1 MNAT1 component of CDK activating kinase\n", "KLHDC8B kelch domain containing 8B\n", "MNT MAX network transcriptional repressor\n", "DEUP1 deuterosome assembly protein 1\n", "MOS MOS proto-oncogene, serine/threonine kinase\n", "MRE11 MRE11 homolog, double strand break repair nuclease\n", "LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2\n", "HUS1B HUS1 checkpoint clamp component B\n", "GIT1 GIT ArfGAP 1\n", "BTBD18 BTB domain containing 18\n", "RGCC regulator of cell cycle\n", "MCTS1 MCTS1 re-initiation and release factor\n", "HIPK2 homeodomain interacting protein kinase 2\n", "PIWIL4 piwi like RNA-mediated gene silencing 4\n", "MSH2 mutS homolog 2\n", "MSH3 mutS homolog 3\n", "MSH4 mutS homolog 4\n", "MSH5 mutS homolog 5\n", "NUPR2 nuclear protein 2, transcriptional regulator\n", "PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3\n", "MSX1 msh homeobox 1\n", "MSX2 msh homeobox 2\n", "SETD2 SET domain containing 2, histone lysine methyltransferase\n", "MAPK15 mitogen-activated protein kinase 15\n", "CHMP4A charged multivesicular body protein 4A\n", "BABAM1 BRISC and BRCA1 A complex member 1\n", "LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4\n", "PYCARD PYD and CARD domain containing\n", "BRD7 bromodomain containing 7\n", "RACGAP1 Rac GTPase activating protein 1\n", "UHRF1 ubiquitin like with PHD and ring finger domains 1\n", "CENPV centromere protein V\n", "FLCN folliculin\n", "PLD6 phospholipase D family member 6\n", "MUC1 mucin 1, cell surface associated\n", "GEN1 GEN1 Holliday junction 5' flap endonuclease\n", "TRIM37 tripartite motif containing 37\n", "MAGEA2B MAGE family member A2B\n", "MX2 MX dynamin like GTPase 2\n", "MAJIN membrane anchored junction protein\n", "MYB MYB proto-oncogene, transcription factor\n", "MYBL1 MYB proto-oncogene like 1\n", "MYBL2 MYB proto-oncogene like 2\n", "CDC14C cell division cycle 14C\n", "MYC MYC proto-oncogene, bHLH transcription factor\n", "THAP5 THAP domain containing 5\n", "ACER2 alkaline ceramidase 2\n", "GADD45B growth arrest and DNA damage inducible beta\n", "MYF5 myogenic factor 5\n", "MYF6 myogenic factor 6\n", "NUGGC nuclear GTPase, germinal center associated\n", "MYH9 myosin heavy chain 9\n", "MYH10 myosin heavy chain 10\n", "MYO6 myosin VI\n", "MYOD1 myogenic differentiation 1\n", "NEK10 NIMA related kinase 10\n", "MYOG myogenin\n", "PPP1R12A protein phosphatase 1 regulatory subunit 12A\n", "PPP1R12B protein phosphatase 1 regulatory subunit 12B\n", "NASP nuclear autoantigenic sperm protein\n", "NUBP1 nucleotide binding protein 1\n", "NBN nibrin\n", "SPICE1 spindle and centriole associated protein 1\n", "DRG1 developmentally regulated GTP binding protein 1\n", "NEDD9 neural precursor cell expressed, developmentally down-regulated 9\n", "NEK1 NIMA related kinase 1\n", "NEK2 NIMA related kinase 2\n", "NEK3 NIMA related kinase 3\n", "NEUROD1 neuronal differentiation 1\n", "NEUROG1 neurogenin 1\n", "PELO pelota mRNA surveillance and ribosome rescue factor\n", "NF2 neurofibromin 2\n", "NFATC1 nuclear factor of activated T cells 1\n", "NFATC2 nuclear factor of activated T cells 2\n", "NFATC3 nuclear factor of activated T cells 3\n", "NFATC4 nuclear factor of activated T cells 4\n", "NFE2L1 nuclear factor, erythroid 2 like 1\n", "BHLHA15 basic helix-loop-helix family member a15\n", "NGF nerve growth factor\n", "NGFR nerve growth factor receptor\n", "ANAPC16 anaphase promoting complex subunit 16\n", "NKX3-1 NK3 homeobox 1\n", "SLC39A5 solute carrier family 39 member 5\n", "CNOT2 CCR4-NOT transcription complex subunit 2\n", "CNOT3 CCR4-NOT transcription complex subunit 3\n", "CNOT4 CCR4-NOT transcription complex subunit 4\n", "NOTCH1 notch receptor 1\n", "NOTCH2 notch receptor 2\n", "CCN3 cellular communication network factor 3\n", "NPAT nuclear protein, coactivator of histone transcription\n", "NPM1 nucleophosmin 1\n", "NPPC natriuretic peptide C\n", "NPR2 natriuretic peptide receptor 2\n", "MIS18A MIS18 kinetochore protein A\n", "NUMA1 nuclear mitotic apparatus protein 1\n", "NUP88 nucleoporin 88\n", "NUP43 nucleoporin 43\n", "ARL8A ADP ribosylation factor like GTPase 8A\n", "POLE3 DNA polymerase epsilon 3, accessory subunit\n", "ODF2 outer dense fiber of sperm tails 2\n", "CHAMP1 chromosome alignment maintaining phosphoprotein 1\n", "OPA1 OPA1 mitochondrial dynamin like GTPase\n", "SEPTIN7 septin 7\n", "ORC1 origin recognition complex subunit 1\n", "ORC2 origin recognition complex subunit 2\n", "ORC4 origin recognition complex subunit 4\n", "ORC5 origin recognition complex subunit 5\n", "OVOL1 ovo like transcriptional repressor 1\n", "P2RX1 purinergic receptor P2X 1\n", "PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1\n", "UHMK1 U2AF homology motif kinase 1\n", "SERPINE1 serpin family E member 1\n", "CYCS cytochrome c, somatic\n", "PAX6 paired box 6\n", "PBX1 PBX homeobox 1\n", "PCM1 pericentriolar material 1\n", "PCNA proliferating cell nuclear antigen\n", "PCNT pericentrin\n", "CHMP1A charged multivesicular body protein 1A\n", "CDK16 cyclin dependent kinase 16\n", "CDK17 cyclin dependent kinase 17\n", "CDK18 cyclin dependent kinase 18\n", "PDCD2 programmed cell death 2\n", "PDE3A phosphodiesterase 3A\n", "DCDC1 doublecortin domain containing 1\n", "REC114 REC114 meiotic recombination protein\n", "CDK8 cyclin dependent kinase 8\n", "PDGFB platelet derived growth factor subunit B\n", "PDGFRB platelet derived growth factor receptor beta\n", "PDK2 pyruvate dehydrogenase kinase 2\n", "TMOD3 tropomodulin 3\n", "E2F7 E2F transcription factor 7\n", "NCAPH2 non-SMC condensin II complex subunit H2\n", "WNT4 Wnt family member 4\n", "SYCE3 synaptonemal complex central element protein 3\n", "CDK14 cyclin dependent kinase 14\n", "PGGT1B protein geranylgeranyltransferase type I subunit beta\n", "ABCB1 ATP binding cassette subfamily B member 1\n", "PNPT1 polyribonucleotide nucleotidyltransferase 1\n", "SENP1 SUMO specific peptidase 1\n", "MIS12 MIS12 kinetochore complex component\n", "FBXL22 F-box and leucine rich repeat protein 22\n", "PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3\n", "ANLN anillin actin binding protein\n", "PIM1 Pim-1 proto-oncogene, serine/threonine kinase\n", "NUP37 nucleoporin 37\n", "ZNF655 zinc finger protein 655\n", "PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1\n", "MOV10L1 Mov10 like RISC complex RNA helicase 1\n", "ANAPC2 anaphase promoting complex subunit 2\n", "CNOT7 CCR4-NOT transcription complex subunit 7\n", "NABP2 nucleic acid binding protein 2\n", "FBXW5 F-box and WD repeat domain containing 5\n", "PKD1 polycystin 1, transient receptor potential channel interacting\n", "PKD2 polycystin 2, transient receptor potential cation channel\n", "ETAA1 ETAA1 activator of ATR kinase\n", "SPIN2A spindlin family member 2A\n", "ASPM assembly factor for spindle microtubules\n", "PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin\n", "PSMC3IP PSMC3 interacting protein\n", "TERB1 telomere repeat binding bouquet formation protein 1\n", "NLE1 notchless homolog 1\n", "GPSM2 G protein signaling modulator 2\n", "PLAGL1 PLAG1 like zinc finger 1\n", "PIMREG PICALM interacting mitotic regulator\n", "TMEM109 transmembrane protein 109\n", "PLK1 polo like kinase 1\n", "DSCC1 DNA replication and sister chromatid cohesion 1\n", "PLRG1 pleiotropic regulator 1\n", "GPR132 G protein-coupled receptor 132\n", "RPA4 replication protein A4\n", "IQGAP3 IQ motif containing GTPase activating protein 3\n", "DDX4 DEAD-box helicase 4\n", "PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1\n", "ANAPC4 anaphase promoting complex subunit 4\n", "PML PML nuclear body scaffold\n", "DNMT3L DNA methyltransferase 3 like\n", "SERTAD1 SERTA domain containing 1\n", "CDIP1 cell death inducing p53 target 1\n", "DDIT4 DNA damage inducible transcript 4\n", "DONSON DNA replication fork stabilization factor DONSON\n", "SLC2A8 solute carrier family 2 member 8\n", "PHF23 PHD finger protein 23\n", "NOP53 NOP53 ribosome biogenesis factor\n", "POLA1 DNA polymerase alpha 1, catalytic subunit\n", "POLD1 DNA polymerase delta 1, catalytic subunit\n", "POLD2 DNA polymerase delta 2, accessory subunit\n", "POLE DNA polymerase epsilon, catalytic subunit\n", "POLE2 DNA polymerase epsilon 2, accessory subunit\n", "FBXL15 F-box and leucine rich repeat protein 15\n", "RAD9B RAD9 checkpoint clamp component B\n", "BRCC3 BRCA1/BRCA2-containing complex subunit 3\n", "POU4F1 POU class 4 homeobox 1\n", "POU4F2 POU class 4 homeobox 2\n", "FSD1 fibronectin type III and SPRY domain containing 1\n", "INO80 INO80 complex ATPase subunit\n", "CCNJ cyclin J\n", "PPARG peroxisome proliferator activated receptor gamma\n", "MED1 mediator complex subunit 1\n", "PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component\n", "PPAT phosphoribosyl pyrophosphate amidotransferase\n", "MAP10 microtubule associated protein 10\n", "PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A\n", "PPM1G protein phosphatase, Mg2+/Mn2+ dependent 1G\n", "PPP1CA protein phosphatase 1 catalytic subunit alpha\n", "PPP1CB protein phosphatase 1 catalytic subunit beta\n", "PPP1CC protein phosphatase 1 catalytic subunit gamma\n", "PPP2CA protein phosphatase 2 catalytic subunit alpha\n", "PIM3 Pim-3 proto-oncogene, serine/threonine kinase\n", "PPP2R1A protein phosphatase 2 scaffold subunit Aalpha\n", "PPP2R2A protein phosphatase 2 regulatory subunit Balpha\n", "PPP2R2B protein phosphatase 2 regulatory subunit Bbeta\n", "PPP2R2C protein phosphatase 2 regulatory subunit Bgamma\n", "PTPA protein phosphatase 2 phosphatase activator\n", "PPP2R5B protein phosphatase 2 regulatory subunit B'beta\n", "PPP3CA protein phosphatase 3 catalytic subunit alpha\n", "PPP3CB protein phosphatase 3 catalytic subunit beta\n", "PPP3CC protein phosphatase 3 catalytic subunit gamma\n", "PPP3R1 protein phosphatase 3 regulatory subunit B, alpha\n", "PPP5C protein phosphatase 5 catalytic subunit\n", "PPP6C protein phosphatase 6 catalytic subunit\n", "MEIOC meiosis specific with coiled-coil domain\n", "PRCC proline rich mitotic checkpoint control factor\n", "PRELP proline and arginine rich end leucine rich repeat protein\n", "PRIM1 DNA primase subunit 1\n", "PRIM2 DNA primase subunit 2\n", "PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1\n", "PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2\n", "PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1\n", "PRKACA protein kinase cAMP-activated catalytic subunit alpha\n", "PRKACB protein kinase cAMP-activated catalytic subunit beta\n", "CEP41 centrosomal protein 41\n", "PKIA cAMP-dependent protein kinase inhibitor alpha\n", "PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha\n", "MPLKIP M-phase specific PLK1 interacting protein\n", "PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta\n", "PRKCA protein kinase C alpha\n", "PRKCD protein kinase C delta\n", "PRKCE protein kinase C epsilon\n", "PRKCB protein kinase C beta\n", "PKN2 protein kinase N2\n", "PRKDC protein kinase, DNA-activated, catalytic subunit\n", "MAPK1 mitogen-activated protein kinase 1\n", "MAPK3 mitogen-activated protein kinase 3\n", "MAPK4 mitogen-activated protein kinase 4\n", "MAPK6 mitogen-activated protein kinase 6\n", "MAPK7 mitogen-activated protein kinase 7\n", "MAPK13 mitogen-activated protein kinase 13\n", "MAP2K1 mitogen-activated protein kinase kinase 1\n", "MAP2K6 mitogen-activated protein kinase kinase 6\n", "BTG4 BTG anti-proliferation factor 4\n", "PRNP prion protein\n", "PROX1 prospero homeobox 1\n", "ALKBH4 alkB homolog 4, lysine demethylase\n", "DAB2IP DAB2 interacting protein\n", "BHLHE41 basic helix-loop-helix family member e41\n", "TET2 tet methylcytosine dioxygenase 2\n", "HMGN5 high mobility group nucleosome binding domain 5\n", "LGMN legumain\n", "HAUS6 HAUS augmin like complex subunit 6\n", "KLK10 kallikrein related peptidase 10\n", "NDE1 nudE neurodevelopment protein 1\n", "ERCC6L ERCC excision repair 6 like, spindle assembly checkpoint helicase\n", "SLC38A9 solute carrier family 38 member 9\n", "PSMA1 proteasome 20S subunit alpha 1\n", "PSMA2 proteasome 20S subunit alpha 2\n", "PSMA3 proteasome 20S subunit alpha 3\n", "PSMA4 proteasome 20S subunit alpha 4\n", "PSMA5 proteasome 20S subunit alpha 5\n", "PSMA6 proteasome 20S subunit alpha 6\n", "PSMA7 proteasome 20S subunit alpha 7\n", "PSMB1 proteasome 20S subunit beta 1\n", "PSMB2 proteasome 20S subunit beta 2\n", "PSMB3 proteasome 20S subunit beta 3\n", "PSMB4 proteasome 20S subunit beta 4\n", "PSMB5 proteasome 20S subunit beta 5\n", "PSMB6 proteasome 20S subunit beta 6\n", "PSMB7 proteasome 20S subunit beta 7\n", "PSMB8 proteasome 20S subunit beta 8\n", "FBXL12 F-box and leucine rich repeat protein 12\n", "PSMB9 proteasome 20S subunit beta 9\n", "PSMB10 proteasome 20S subunit beta 10\n", "PSMC1 proteasome 26S subunit, ATPase 1\n", "PSMC2 proteasome 26S subunit, ATPase 2\n", "PSMC3 proteasome 26S subunit, ATPase 3\n", "PSMC4 proteasome 26S subunit, ATPase 4\n", "PSMC5 proteasome 26S subunit, ATPase 5\n", "PSMC6 proteasome 26S subunit, ATPase 6\n", "PSMD1 proteasome 26S subunit, non-ATPase 1\n", "PSMD2 proteasome 26S subunit, non-ATPase 2\n", "PSMD3 proteasome 26S subunit, non-ATPase 3\n", "PSMD4 proteasome 26S subunit, non-ATPase 4\n", "PSMD5 proteasome 26S subunit, non-ATPase 5\n", "HAUS3 HAUS augmin like complex subunit 3\n", "PSMD7 proteasome 26S subunit, non-ATPase 7\n", "PSMD8 proteasome 26S subunit, non-ATPase 8\n", "PSMD10 proteasome 26S subunit, non-ATPase 10\n", "PSMD11 proteasome 26S subunit, non-ATPase 11\n", "PSMD9 proteasome 26S subunit, non-ATPase 9\n", "PSMD13 proteasome 26S subunit, non-ATPase 13\n", "PAGR1 PAXIP1 associated glutamate rich protein 1\n", "PSME1 proteasome activator subunit 1\n", "PSME2 proteasome activator subunit 2\n", "PSMD12 proteasome 26S subunit, non-ATPase 12\n", "CNTLN centlein\n", "PTCH1 patched 1\n", "PTEN phosphatase and tensin homolog\n", "BOD1L2 biorientation of chromosomes in cell division 1 like 2\n", "NSUN2 NOP2/Sun RNA methyltransferase 2\n", "NCAPG2 non-SMC condensin II complex subunit G2\n", "KLLN killin, p53 regulated DNA replication inhibitor\n", "PTGS2 prostaglandin-endoperoxide synthase 2\n", "TTC19 tetratricopeptide repeat domain 19\n", "PTK6 protein tyrosine kinase 6\n", "SPDL1 spindle apparatus coiled-coil protein 1\n", "CHTF8 chromosome transmission fidelity factor 8\n", "PTPN3 protein tyrosine phosphatase non-receptor type 3\n", "PTPN6 protein tyrosine phosphatase non-receptor type 6\n", "HAUS4 HAUS augmin like complex subunit 4\n", "PTPN11 protein tyrosine phosphatase non-receptor type 11\n", "CEP120 centrosomal protein 120\n", "PTPRC protein tyrosine phosphatase receptor type C\n", "PTPRK protein tyrosine phosphatase receptor type K\n", "TXNL4B thioredoxin like 4B\n", "RAD1 RAD1 checkpoint DNA exonuclease\n", "TIPIN TIMELESS interacting protein\n", "OR2A4 olfactory receptor family 2 subfamily A member 4\n", "BANP BTG3 associated nuclear protein\n", "MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator\n", "PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1\n", "AURKAIP1 aurora kinase A interacting protein 1\n", "CDC73 cell division cycle 73\n", "LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1\n", "MUL1 mitochondrial E3 ubiquitin protein ligase 1\n", "CEP97 centrosomal protein 97\n", "PHIP pleckstrin homology domain interacting protein\n", "WDR62 WD repeat domain 62\n", "USP47 ubiquitin specific peptidase 47\n", "RAD9A RAD9 checkpoint clamp component A\n", "RAD17 RAD17 checkpoint clamp loader component\n", "RAD21 RAD21 cohesin complex component\n", "RAD23A RAD23 homolog A, nucleotide excision repair protein\n", "RAD51 RAD51 recombinase\n", "RAD51C RAD51 paralog C\n", "CCNJL cyclin J like\n", "RAD51B RAD51 paralog B\n", "RAD51D RAD51 paralog D\n", "RAD52 RAD52 homolog, DNA repair protein\n", "RNASEH2B ribonuclease H2 subunit B\n", "MOK MOK protein kinase\n", "RALA RAS like proto-oncogene A\n", "RALB RAS like proto-oncogene B\n", "RAN RAN, member RAS oncogene family\n", "RANBP1 RAN binding protein 1\n", "ZWILCH zwilch kinetochore protein\n", "EGLN3 egl-9 family hypoxia inducible factor 3\n", "RARA retinoic acid receptor alpha\n", "CHMP6 charged multivesicular body protein 6\n", "ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1\n", "MCPH1 microcephalin 1\n", "RASA1 RAS p21 protein activator 1\n", "RB1 RB transcriptional corepressor 1\n", "RBBP4 RB binding protein 4, chromatin remodeling factor\n", "IFT57 intraflagellar transport 57\n", "RBBP7 RB binding protein 7, chromatin remodeling factor\n", "RBBP8 RB binding protein 8, endonuclease\n", "RBL1 RB transcriptional corepressor like 1\n", "RBL2 RB transcriptional corepressor like 2\n", "SMC6 structural maintenance of chromosomes 6\n", "OPN1LW opsin 1, long wave sensitive\n", "RDX radixin\n", "MZT1 mitotic spindle organizing protein 1\n", "PIWIL2 piwi like RNA-mediated gene silencing 2\n", "CEP192 centrosomal protein 192\n", "C11orf80 chromosome 11 open reading frame 80\n", "UPF1 UPF1 RNA helicase and ATPase\n", "RFC1 replication factor C subunit 1\n", "RFC2 replication factor C subunit 2\n", "RFC3 replication factor C subunit 3\n", "RFC4 replication factor C subunit 4\n", "FIGN fidgetin, microtubule severing factor\n", "CHMP4B charged multivesicular body protein 4B\n", "RFC5 replication factor C subunit 5\n", "RFPL1 ret finger protein like 1\n", "HAUS2 HAUS augmin like complex subunit 2\n", "CDCA8 cell division cycle associated 8\n", "THAP1 THAP domain containing 1\n", "SUV39H2 suppressor of variegation 3-9 homolog 2\n", "RGS2 regulator of G protein signaling 2\n", "MSTO1 misato mitochondrial distribution and morphology regulator 1\n", "E2F8 E2F transcription factor 8\n", "RFWD3 ring finger and WD repeat domain 3\n", "RHEB Ras homolog, mTORC1 binding\n", "CEP55 centrosomal protein 55\n", "RING1 ring finger protein 1\n", "PRMT6 protein arginine methyltransferase 6\n", "RIF1 replication timing regulatory factor 1\n", "PBRM1 polybromo 1\n", "RNF2 ring finger protein 2\n", "APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2\n", "RNF4 ring finger protein 4\n", "ARL8B ADP ribosylation factor like GTPase 8B\n", "RCBTB1 RCC1 and BTB domain containing protein 1\n", "FANCI FA complementation group I\n", "FBXO31 F-box protein 31\n", "SNX18 sorting nexin 18\n", "EHMT1 euchromatic histone lysine methyltransferase 1\n", "STEAP3 STEAP3 metalloreductase\n", "ROBO1 roundabout guidance receptor 1\n", "ROCK1 Rho associated coiled-coil containing protein kinase 1\n", "SPRED1 sprouty related EVH1 domain containing 1\n", "YY1AP1 YY1 associated protein 1\n", "EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4\n", "KDM8 lysine demethylase 8\n", "RPA1 replication protein A1\n", "RPA2 replication protein A2\n", "RPA3 replication protein A3\n", "CSPP1 centrosome and spindle pole associated protein 1\n", "NUDT15 nudix hydrolase 15\n", "NEK11 NIMA related kinase 11\n", "TUBAL3 tubulin alpha like 3\n", "BORA BORA aurora kinase A activator\n", "FBXW7 F-box and WD repeat domain containing 7\n", "CCNI2 cyclin I family member 2\n", "RPL24 ribosomal protein L24\n", "RPL26 ribosomal protein L26\n", "MAP9 microtubule associated protein 9\n", "SMIM22 small integral membrane protein 22\n", "MCMBP minichromosome maintenance complex binding protein\n", "MIS18BP1 MIS18 binding protein 1\n", "MNS1 meiosis specific nuclear structural 1\n", "EXD1 exonuclease 3'-5' domain containing 1\n", "FBXL8 F-box and leucine rich repeat protein 8\n", "ATAD5 ATPase family AAA domain containing 5\n", "RPS6 ribosomal protein S6\n", "RPS6KA1 ribosomal protein S6 kinase A1\n", "RPS6KA2 ribosomal protein S6 kinase A2\n", "RPS6KA3 ribosomal protein S6 kinase A3\n", "RPS6KB1 ribosomal protein S6 kinase B1\n", "HJURP Holliday junction recognition protein\n", "CCNP cyclin P\n", "RPS15A ribosomal protein S15a\n", "PIDD1 p53-induced death domain protein 1\n", "TUBA3E tubulin alpha 3e\n", "CEP76 centrosomal protein 76\n", "JADE1 jade family PHD finger 1\n", "MCM10 minichromosome maintenance 10 replication initiation factor\n", "RRM1 ribonucleotide reductase catalytic subunit M1\n", "RRM2 ribonucleotide reductase regulatory subunit M2\n", "RTKN rhotekin\n", "WDR76 WD repeat domain 76\n", "CLIP1 CAP-Gly domain containing linker protein 1\n", "DSN1 DSN1 component of MIS12 kinetochore complex\n", "SPRED3 sprouty related EVH1 domain containing 3\n", "RYR1 ryanodine receptor 1\n", "EHD2 EH domain containing 2\n", "ANKRD53 ankyrin repeat domain 53\n", "SORT1 sortilin 1\n", "PIK3R4 phosphoinositide-3-kinase regulatory subunit 4\n", "S100A8 S100 calcium binding protein A8\n", "S100A9 S100 calcium binding protein A9\n", "PHC3 polyhomeotic homolog 3\n", "STRADB STE20 related adaptor beta\n", "CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1\n", "FBXL18 F-box and leucine rich repeat protein 18\n", "MAPK12 mitogen-activated protein kinase 12\n", "CCL2 C-C motif chemokine ligand 2\n", "CCL8 C-C motif chemokine ligand 8\n", "TUBA4B tubulin alpha 4b\n", "SMPD3 sphingomyelin phosphodiesterase 3\n", "TRIM36 tripartite motif containing 36\n", "TERB2 telomere repeat binding bouquet formation protein 2\n", "TUBB8B tubulin beta 8B\n", "SDCBP syndecan binding protein\n", "RBM38 RNA binding motif protein 38\n", "VCPIP1 valosin containing protein interacting protein 1\n", "HAUS7 HAUS augmin like complex subunit 7\n", "ZNF703 zinc finger protein 703\n", "CNOT11 CCR4-NOT transcription complex subunit 11\n", "SETMAR SET domain and mariner transposase fusion gene\n", "SFPQ splicing factor proline and glutamine rich\n", "SFRP1 secreted frizzled related protein 1\n", "CENPT centromere protein T\n", "ATF5 activating transcription factor 5\n", "SRSF5 serine and arginine rich splicing factor 5\n", "PHLDA1 pleckstrin homology like domain family A member 1\n", "CTC1 CST telomere replication complex component 1\n", "DBF4B DBF4 zinc finger B\n", "MYO19 myosin XIX\n", "CEP290 centrosomal protein 290\n", "TUBB tubulin beta class I\n", "VASH1 vasohibin 1\n", "PRR5 proline rich 5\n", "C14orf39 chromosome 14 open reading frame 39\n", "SHH sonic hedgehog signaling molecule\n", "MUS81 MUS81 structure-specific endonuclease subunit\n", "SHOX2 short stature homeobox 2\n", "SIAH1 siah E3 ubiquitin protein ligase 1\n", "SIAH2 siah E3 ubiquitin protein ligase 2\n", "NLRP1 NLR family pyrin domain containing 1\n", "NAA50 N-alpha-acetyltransferase 50, NatE catalytic subunit\n", "STIL STIL centriolar assembly protein\n", "SIPA1 signal-induced proliferation-associated 1\n", "SIX1 SIX homeobox 1\n", "SIX3 SIX homeobox 3\n", "SKI SKI proto-oncogene\n", "SKIL SKI like proto-oncogene\n", "SKP1 S-phase kinase associated protein 1\n", "SKP2 S-phase kinase associated protein 2\n", "KHDC1L KH domain containing 1 like\n", "PRPF40A pre-mRNA processing factor 40 homolog A\n", "URGCP upregulator of cell proliferation\n", "CEP164 centrosomal protein 164\n", "CARD8 caspase recruitment domain family member 8\n", "CEP63 centrosomal protein 63\n", "SLC6A4 solute carrier family 6 member 4\n", "MAPRE1 microtubule associated protein RP/EB family member 1\n", "MAPRE3 microtubule associated protein RP/EB family member 3\n", "PLA2R1 phospholipase A2 receptor 1\n", "SIRT2 sirtuin 2\n", "YJU2 YJU2 splicing factor homolog\n", "CDK5RAP3 CDK5 regulatory subunit associated protein 3\n", "NDC1 NDC1 transmembrane nucleoporin\n", "SNW1 SNW domain containing 1\n", "SLC16A1 solute carrier family 16 member 1\n", "SLF2 SMC5-SMC6 complex localization factor 2\n", "P2RX2 purinergic receptor P2X 2\n", "TRIM32 tripartite motif containing 32\n", "CEP72 centrosomal protein 72\n", "INTS13 integrator complex subunit 13\n", "CHTF18 chromosome transmission fidelity factor 18\n", "EPC1 enhancer of polycomb homolog 1\n", "TPX2 TPX2 microtubule nucleation factor\n", "SNAI2 snail family transcriptional repressor 2\n", "CHFR checkpoint with forkhead and ring finger domains\n", "CEP70 centrosomal protein 70\n", "PAXIP1 PAX interacting protein 1\n", "CCAR1 cell division cycle and apoptosis regulator 1\n", "SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1\n", "NINL ninein like\n", "DMRTC2 DMRT like family C2\n", "CDK5RAP2 CDK5 regulatory subunit associated protein 2\n", "CEP295NL CEP295 N-terminal like\n", "SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3\n", "SMO smoothened, frizzled class receptor\n", "CEP131 centrosomal protein 131\n", "CEP152 centrosomal protein 152\n", "SNAI1 snail family transcriptional repressor 1\n", "REEP4 receptor accessory protein 4\n", "PRR11 proline rich 11\n", "SNCA synuclein alpha\n", "CLSPN claspin\n", "KIF13A kinesin family member 13A\n", "RIOK2 RIO kinase 2\n", "CDCA5 cell division cycle associated 5\n", "CNOT1 CCR4-NOT transcription complex subunit 1\n", "TXLNG taxilin gamma\n", "FIGNL1 fidgetin like 1\n", "MYO16 myosin XVI\n", "PCID2 PCI domain containing 2\n", "KDM1A lysine demethylase 1A\n", "PIWIL3 piwi like RNA-mediated gene silencing 3\n", "SOD1 superoxide dismutase 1\n", "SON SON DNA and RNA binding protein\n", "MITD1 microtubule interacting and trafficking domain containing 1\n", "SOX2 SRY-box transcription factor 2\n", "SOX4 SRY-box transcription factor 4\n", "SOX9 SRY-box transcription factor 9\n", "PDS5B PDS5 cohesin associated factor B\n", "SOX11 SRY-box transcription factor 11\n", "SOX15 SRY-box transcription factor 15\n", "SP100 SP100 nuclear antigen\n", "WAPL WAPL cohesin release factor\n", "CENPJ centromere protein J\n", "DIS3L2 DIS3 like 3'-5' exoribonuclease 2\n", "SPAST spastin\n", "PPP2R2D protein phosphatase 2 regulatory subunit Bdelta\n", "TOPAZ1 testis and ovary specific PAZ domain containing 1\n", "TRIM35 tripartite motif containing 35\n", "ACTR10 actin related protein 10\n", "SPTBN1 spectrin beta, non-erythrocytic 1\n", "CDK19 cyclin dependent kinase 19\n", "SRC SRC proto-oncogene, non-receptor tyrosine kinase\n", "TSPYL2 TSPY like 2\n", "HDAC8 histone deacetylase 8\n", "PBK PDZ binding kinase\n", "PERP p53 apoptosis effector related to PMP22\n", "SRF serum response factor\n", "CUL9 cullin 9\n", "SRPK2 SRSF protein kinase 2\n", "TRIM21 tripartite motif containing 21\n", "CLASP2 cytoplasmic linker associated protein 2\n", "POGZ pogo transposable element derived with ZNF domain\n", "STOX1 storkhead box 1\n", "PHF8 PHD finger protein 8\n", "SMOC2 SPARC related modular calcium binding 2\n", "KMT2E lysine methyltransferase 2E (inactive)\n", "SMC5 structural maintenance of chromosomes 5\n", "NEDD1 NEDD1 gamma-tubulin ring complex targeting factor\n", "SSTR5 somatostatin receptor 5\n", "BIN3 bridging integrator 3\n", "ANKLE2 ankyrin repeat and LEM domain containing 2\n", "CENPK centromere protein K\n", "RCC2 regulator of chromosome condensation 2\n", "SEPTIN6 septin 6\n", "STAT3 signal transducer and activator of transcription 3\n", "STAT5B signal transducer and activator of transcription 5B\n", "RRAGC Ras related GTP binding C\n", "CCNY cyclin Y\n", "GJD4 gap junction protein delta 4\n", "TTLL12 tubulin tyrosine ligase like 12\n", "NEK4 NIMA related kinase 4\n", "ABRAXAS2 abraxas 2, BRISC complex subunit\n", "AURKA aurora kinase A\n", "LPIN1 lipin 1\n", "CDKL5 cyclin dependent kinase like 5\n", "CEP68 centrosomal protein 68\n", "STK10 serine/threonine kinase 10\n", "AURKC aurora kinase C\n", "STK11 serine/threonine kinase 11\n", "LIN37 lin-37 DREAM MuvB core complex component\n", "KLHL9 kelch like family member 9\n", "NCAPG non-SMC condensin I complex subunit G\n", "FBXL7 F-box and leucine rich repeat protein 7\n", "UBXN2B UBX domain protein 2B\n", "PSME4 proteasome activator subunit 4\n", "NSFL1C NSFL1 cofactor\n", "SULT1A3 sulfotransferase family 1A member 3\n", "RRS1 ribosome biogenesis regulator 1 homolog\n", "DPEP3 dipeptidase 3\n", "SUV39H1 suppressor of variegation 3-9 homolog 1\n", "SVIL supervillin\n", "SYCP1 synaptonemal complex protein 1\n", "PLCB1 phospholipase C beta 1\n", "PDS5A PDS5 cohesin associated factor A\n", "BOP1 BOP1 ribosomal biogenesis factor\n", "TACC1 transforming acidic coiled-coil containing protein 1\n", "ADAM17 ADAM metallopeptidase domain 17\n", "TAF1 TATA-box binding protein associated factor 1\n", "TAF2 TATA-box binding protein associated factor 2\n", "TAF6 TATA-box binding protein associated factor 6\n", "MLST8 MTOR associated protein, LST8 homolog\n", "TAF10 TATA-box binding protein associated factor 10\n", "MGA MAX dimerization protein MGA\n", "TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor\n", "KLHL18 kelch like family member 18\n", "TBX1 T-box transcription factor 1\n", "TBCD tubulin folding cofactor D\n", "TBCE tubulin folding cofactor E\n", "FBXW11 F-box and WD repeat domain containing 11\n", "TBX2 T-box transcription factor 2\n", "UBR2 ubiquitin protein ligase E3 component n-recognin 2\n", "TBX3 T-box transcription factor 3\n", "NCAPD3 non-SMC condensin II complex subunit D3\n", "TCF7L2 transcription factor 7 like 2\n", "TENT4B terminal nucleotidyltransferase 4B\n", "USP22 ubiquitin specific peptidase 22\n", "TTC28 tetratricopeptide repeat domain 28\n", "CLASP1 cytoplasmic linker associated protein 1\n", "SUN1 Sad1 and UNC84 domain containing 1\n", "HAUS5 HAUS augmin like complex subunit 5\n", "RNF212 ring finger protein 212\n", "OBSL1 obscurin like cytoskeletal adaptor 1\n", "PPP1R13B protein phosphatase 1 regulatory subunit 13B\n", "ESX1 ESX homeobox 1\n", "DYNLT3 dynein light chain Tctex-type 3\n", "DYNLT1 dynein light chain Tctex-type 1\n", "RRP8 ribosomal RNA processing 8\n", "AZI2 5-azacytidine induced 2\n", "SPECC1L sperm antigen with calponin homology and coiled-coil domains 1 like\n", "MAU2 MAU2 sister chromatid cohesion factor\n", "TEX15 testis expressed 15, meiosis and synapsis associated\n", "TEX14 testis expressed 14, intercellular bridge forming factor\n", "TEX12 testis expressed 12\n", "TEX11 testis expressed 11\n", "TEP1 telomerase associated protein 1\n", "NCAPH non-SMC condensin I complex subunit H\n", "TERF2 telomeric repeat binding factor 2\n", "TDRD1 tudor domain containing 1\n", "TERT telomerase reverse transcriptase\n", "TERF1 telomeric repeat binding factor 1\n", "CTDNEP1 CTD nuclear envelope phosphatase 1\n", "TFAP4 transcription factor AP-4\n", "NR2F2 nuclear receptor subfamily 2 group F member 2\n", "TFDP1 transcription factor Dp-1\n", "SIRT1 sirtuin 1\n", "TFDP2 transcription factor Dp-2\n", "KHDC1 KH domain containing 1\n", "ITGB3BP integrin subunit beta 3 binding protein\n", "TGFA transforming growth factor alpha\n", "TGFB1 transforming growth factor beta 1\n", "TGFB2 transforming growth factor beta 2\n", "RYBP RING1 and YY1 binding protein\n", "TGFBR1 transforming growth factor beta receptor 1\n", "DDIAS DNA damage induced apoptosis suppressor\n", "TGM1 transglutaminase 1\n", "LMOD3 leiomodin 3\n", "TARDBP TAR DNA binding protein\n", "THBS1 thrombospondin 1\n", "TIMP2 TIMP metallopeptidase inhibitor 2\n", "NACC2 NACC family member 2\n", "CBX5 chromobox 5\n", "SUSD2 sushi domain containing 2\n", "BRD4 bromodomain containing 4\n", "PES1 pescadillo ribosomal biogenesis factor 1\n", "NR2E1 nuclear receptor subfamily 2 group E member 1\n", "MEPCE methylphosphate capping enzyme\n", "TAS1R2 taste 1 receptor member 2\n", "NANOS3 nanos C2HC-type zinc finger 3\n", "KIF4B kinesin family member 4B\n", "ZFYVE26 zinc finger FYVE-type containing 26\n", "TNF tumor necrosis factor\n", "TNFAIP3 TNF alpha induced protein 3\n", "SCRIB scribble planar cell polarity protein\n", "SUZ12 SUZ12 polycomb repressive complex 2 subunit\n", "MORC3 MORC family CW-type zinc finger 3\n", "PARD3 par-3 family cell polarity regulator\n", "SKA1 spindle and kinetochore associated complex subunit 1\n", "TOP2A DNA topoisomerase II alpha\n", "TOP2B DNA topoisomerase II beta\n", "TOP3A DNA topoisomerase III alpha\n", "TP53 tumor protein p53\n", "TP53BP1 tumor protein p53 binding protein 1\n", "TP53BP2 tumor protein p53 binding protein 2\n", "TP73 tumor protein p73\n", "TPD52L1 TPD52 like 1\n", "CDK20 cyclin dependent kinase 20\n", "TPR translocated promoter region, nuclear basket protein\n", "GTPBP4 GTP binding protein 4\n", "TRAF2 TNF receptor associated factor 2\n", "METTL3 methyltransferase like 3\n", "CASP14 caspase 14\n", "CCNDBP1 cyclin D1 binding protein 1\n", "ORC6 origin recognition complex subunit 6\n", "ORC3 origin recognition complex subunit 3\n", "CD2AP CD2 associated protein\n", "STXBP4 syntaxin binding protein 4\n", "PHLDA3 pleckstrin homology like domain family A member 3\n", "SPO11 SPO11 initiator of meiotic double stranded breaks\n", "TSC1 TSC complex subunit 1\n", "TSC2 TSC complex subunit 2\n", "TSG101 tumor susceptibility 101\n", "NUP62 nucleoporin 62\n", "HEPACAM2 HEPACAM family member 2\n", "RABGAP1 RAB GTPase activating protein 1\n", "PPP1R15A protein phosphatase 1 regulatory subunit 15A\n", "POLA2 DNA polymerase alpha 2, accessory subunit\n", "TTK TTK protein kinase\n", "TTN titin\n", "TUBA4A tubulin alpha 4a\n", "TUBB2A tubulin beta 2A class IIa\n", "TUBG1 tubulin gamma 1\n", "CASP12 caspase 12 (gene/pseudogene)\n", "HIRA histone cell cycle regulator\n", "TWIST1 twist family bHLH transcription factor 1\n", "TYMS thymidylate synthetase\n", "TUBB1 tubulin beta 1 class VI\n", "HEPACAM hepatic and glial cell adhesion molecule\n", "UBB ubiquitin B\n", "UBE2B ubiquitin conjugating enzyme E2 B\n", "UBE2D1 ubiquitin conjugating enzyme E2 D1\n", "RPRM reprimo, TP53 dependent G2 arrest mediator homolog\n", "GSPT2 G1 to S phase transition 2\n", "UBE2E2 ubiquitin conjugating enzyme E2 E2\n", "UBE2E1 ubiquitin conjugating enzyme E2 E1\n", "UBE2I ubiquitin conjugating enzyme E2 I\n", "UBE2L3 ubiquitin conjugating enzyme E2 L3\n", "ANAPC1 anaphase promoting complex subunit 1\n", "EID1 EP300 interacting inhibitor of differentiation 1\n", "SPIN2B spindlin family member 2B\n", "BCL2L13 BCL2 like 13\n", "MTCH1 mitochondrial carrier 1\n", "TAF1L TATA-box binding protein associated factor 1 like\n", "UVRAG UV radiation resistance associated\n", "SMYD3 SET and MYND domain containing 3\n", "TEX19 testis expressed 19\n", "VCP valosin containing protein\n", "TOM1L2 target of myb1 like 2 membrane trafficking protein\n", "AEN apoptosis enhancing nuclease\n", "VRK1 VRK serine/threonine kinase 1\n", "CEP85 centrosomal protein 85\n", "CYP26B1 cytochrome P450 family 26 subfamily B member 1\n", "DIABLO diablo IAP-binding mitochondrial protein\n", "WEE1 WEE1 G2 checkpoint kinase\n", "ASAH2 N-acylsphingosine amidohydrolase 2\n", "WNT5A Wnt family member 5A\n", "WNT10B Wnt family member 10B\n", "WNT9A Wnt family member 9A\n", "WRN WRN RecQ like helicase\n", "XBP1 X-box binding protein 1\n", "BCCIP BRCA2 and CDKN1A interacting protein\n", "XDH xanthine dehydrogenase\n", "MARCHF7 membrane associated ring-CH-type finger 7\n", "POLE4 DNA polymerase epsilon 4, accessory subunit\n", "XK X-linked Kx blood group\n", "YTHDC2 YTH domain containing 2\n", "XPC XPC complex subunit, DNA damage recognition and repair factor\n", "NIBAN2 niban apoptosis regulator 2\n", "DCLRE1B DNA cross-link repair 1B\n", "XRCC1 X-ray repair cross complementing 1\n", "XRCC2 X-ray repair cross complementing 2\n", "XRCC3 X-ray repair cross complementing 3\n", "NABP1 nucleic acid binding protein 1\n", "XPO1 exportin 1\n", "NSMCE2 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase\n", "YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon\n", "YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma\n", "OPN1MW2 opsin 1, medium wave sensitive 2\n", "ZNF16 zinc finger protein 16\n", "FBXO43 F-box protein 43\n", "FMN2 formin 2\n", "MRPL41 mitochondrial ribosomal protein L41\n", "FAM9A family with sequence similarity 9 member A\n", "FAM9B family with sequence similarity 9 member B\n", "FAM9C family with sequence similarity 9 member C\n", "KIF18B kinesin family member 18B\n", "EME1 essential meiotic structure-specific endonuclease 1\n", "PCGF2 polycomb group ring finger 2\n", "ZBTB17 zinc finger and BTB domain containing 17\n", "TDRD9 tudor domain containing 9\n", "CDK15 cyclin dependent kinase 15\n", "RNF112 ring finger protein 112\n", "MDM1 Mdm1 nuclear protein\n", "TCIM transcriptional and immune response regulator\n", "MEIKIN meiotic kinetochore factor\n", "CDK11A cyclin dependent kinase 11A\n", "KIF4A kinesin family member 4A\n", "SPIRE1 spire type actin nucleation factor 1\n", "ZNF207 zinc finger protein 207\n", "SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1\n", "ZNF318 zinc finger protein 318\n", "TIPRL TOR signaling pathway regulator\n", "KCTD11 potassium channel tetramerization domain containing 11\n", "INTS3 integrator complex subunit 3\n", "SMYD2 SET and MYND domain containing 2\n", "PTP4A1 protein tyrosine phosphatase 4A1\n", "EVI5 ecotropic viral integration site 5\n", "GDPD5 glycerophosphodiester phosphodiesterase domain containing 5\n", "PRDM9 PR/SET domain 9\n", "PRDM11 PR/SET domain 11\n", "EFHC1 EF-hand domain containing 1\n", "BTG2 BTG anti-proliferation factor 2\n", "PSMG2 proteasome assembly chaperone 2\n", "NDEL1 nudE neurodevelopment protein 1 like 1\n", "ALMS1 ALMS1 centrosome and basal body associated protein\n", "KIF15 kinesin family member 15\n", "RSPH1 radial spoke head component 1\n", "TUBA1A tubulin alpha 1a\n", "LMLN leishmanolysin like peptidase\n", "CCNL1 cyclin L1\n", "PDXP pyridoxal phosphatase\n", "FAM83D family with sequence similarity 83 member D\n", "CAB39L calcium binding protein 39 like\n", "CDT1 chromatin licensing and DNA replication factor 1\n", "SHCBP1L SHC binding and spindle associated 1 like\n", "NLRP2B NLR family pyrin domain containing 2B\n", "PCBP4 poly(rC) binding protein 4\n", "BAG6 BAG cochaperone 6\n", "DDX39B DExD-box helicase 39B\n", "PCNP PEST proteolytic signal containing nuclear protein\n", "CCNL2 cyclin L2\n", "FZD3 frizzled class receptor 3\n", "CHMP1B charged multivesicular body protein 1B\n", "KAT6A lysine acetyltransferase 6A\n", "NR4A3 nuclear receptor subfamily 4 group A member 3\n", "GJC2 gap junction protein gamma 2\n", "PSMB11 proteasome subunit beta 11\n", "NUP214 nucleoporin 214\n", "ZMIZ1 zinc finger MIZ-type containing 1\n", "SAPCD2 suppressor APC domain containing 2\n", "SELENON selenoprotein N\n", "REEP3 receptor accessory protein 3\n", "NLRP3 NLR family pyrin domain containing 3\n", "FOSL1 FOS like 1, AP-1 transcription factor subunit\n", "CUL5 cullin 5\n", "M1AP meiosis 1 associated protein\n", "AAAS aladin WD repeat nucleoporin\n", "YEATS4 YEATS domain containing 4\n", "HMGA2 high mobility group AT-hook 2\n", "CDK2AP1 cyclin dependent kinase 2 associated protein 1\n", "TMEM14B transmembrane protein 14B\n", "MED25 mediator complex subunit 25\n", "SASS6 SAS-6 centriolar assembly protein\n", "SPDYA speedy/RINGO cell cycle regulator family member A\n", "LACRT lacritin\n", "SKA3 spindle and kinetochore associated complex subunit 3\n", "KAT14 lysine acetyltransferase 14\n" ] } ], "source": [ "for geneid in geneids: # geneids associated with cell-cycle\n", " nt = GENEID2NT.get(geneid, None)\n", " if nt is not None:\n", " print(\"{Symbol:<10} {desc}\".format(\n", " Symbol = nt.Symbol, \n", " desc = nt.description))" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "Copyright 2016-present, DV Klopfenstein, Haibao Tang. All rights reserved." ] } ], "metadata": { "kernelspec": { "display_name": "Python 3", "language": "python", "name": "python3" }, "language_info": { "codemirror_mode": { "name": "ipython", "version": 3 }, "file_extension": ".py", "mimetype": "text/x-python", "name": "python", "nbconvert_exporter": "python", "pygments_lexer": "ipython3", "version": "3.6.7" } }, "nbformat": 4, "nbformat_minor": 1 }